2024
Study protocol: Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform
Collaborative T, Williamson E, Tazare J, Bhaskaran K, Walker A, McDonald H, Tomlinson L, Bacon S, Bates C, Curtis H, Forbes H, Minassian C, Morton C, Nightingale E, Mehrkar A, Evans D, Nicholson B, Leon D, Inglesby P, MacKenna B, Cockburn J, Davies N, Hulme W, Morley J, Douglas I, Rentsch C, Mathur R, Wong A, Schultze A, Croker R, Parry J, Hester F, Harper S, Perera R, Grieve R, Harrison D, Steyerberg E, Eggo R, Diaz-Ordaz K, Keogh R, Evans S, Smeeth L, Goldacre B. Study protocol: Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform. Wellcome Open Research 2024, 5: 243. PMID: 39931522, PMCID: PMC11809169, DOI: 10.12688/wellcomeopenres.16353.2.Peer-Reviewed Original ResearchRisk prediction modelPrimary care electronic health records dataElectronic health record dataTime-varying measuresHealth record dataRisk of poor outcomesOpenSAFELY platformChronic disease settingsRestricted social contactDeath dataCOVID-19 related deathsWorld Health OrganizationCohort approachCOVID-19 deathsRecord dataCOVID-19Population of adult patientsHealth OrganizationRisk predictionOpenSAFELYSocial contactPerceived RiskPolicy changesRelated deathsAdult patientsEditor's Choice – Results of SurVeil Versus IN.PACT Admiral Paclitaxel Coated Balloons in Femoropopliteal Arteries: 24 Month Outcomes of the Randomised TRANSCEND Study
Brodmann M, Gray W, Schneider P, Kurzmann-Guetl K, Schweiger L, Zeller T, Thieme M, Kilaru S, Bachinsky W, Feldman R, Holden A, Varcoe R, Lansky A, Rosenfield K, Investigators T. Editor's Choice – Results of SurVeil Versus IN.PACT Admiral Paclitaxel Coated Balloons in Femoropopliteal Arteries: 24 Month Outcomes of the Randomised TRANSCEND Study. European Journal Of Vascular And Endovascular Surgery 2024, 69: 452-462. PMID: 39615582, DOI: 10.1016/j.ejvs.2024.11.351.Peer-Reviewed Original ResearchFemoropopliteal artery diseasePrimary safetyPrimary patencyTRANSCEND studiesNon-inferiorityArtery diseaseRutherford stage 2Procedure related deathNon-inferiority clinical studyTarget lesion revascularisationTarget vessel revascularisationPaclitaxel coated balloonTarget limb amputationPrimary efficacyEfficacy endpointBinary restenosisClinical studiesFemoropopliteal arteriesSecondary outcomesRelated deathsCoated balloonsPatientsMonthsEfficacyPatency
2023
Do adolescent trajectories of riding with an impaired driver and driving impaired predict similar behaviors in early adulthood?
Li K, Camenga D, Banz B, Zuniga V, Iannotti R, Grayton C, Dziura J, Haynie D, Simons-Morton B, Curry L, Vaca F. Do adolescent trajectories of riding with an impaired driver and driving impaired predict similar behaviors in early adulthood? Accident Analysis & Prevention 2023, 193: 107304. PMID: 37729749, PMCID: PMC10591885, DOI: 10.1016/j.aap.2023.107304.Peer-Reviewed Original ResearchConceptsDWI behaviorEarly adulthoodMarijuana useImpaired driversAnnual assessment wavesNEXT Generation Health StudyAdolescent trajectoriesLatent class analysis studyRepresentative longitudinal studyAssessment wavesNext participantHigher engagementTrajectory classesLongitudinal studyProspective associationsMixed-methods studyLatest followWork hoursRelated deathsLong-term effectsAdulthoodInterview 4Health StudyHealth statusGrade cohorts
2022
COVID-19 susceptibility and clinical outcomes in autoimmune inflammatory rheumatic diseases (AIRDs): a systematic review and meta-analysis.
Shin J, Kim S, Lee M, Kim M, Lee S, Park S, Shin Y, Yang J, Song J, Moon S, Kim S, Park Y, Suh D, Yang J, Cho S, Jin H, Hong S, Won H, Kronbichler A, Koyanagi A, Jacob L, Hwang J, Tizaoui K, Lee K, Kim J, Yon D, Smith L. COVID-19 susceptibility and clinical outcomes in autoimmune inflammatory rheumatic diseases (AIRDs): a systematic review and meta-analysis. European Review For Medical And Pharmacological Sciences 2022, 26: 3760-3770. PMID: 35647859, DOI: 10.26355/eurrev_202205_28873.Peer-Reviewed Original ResearchConceptsAutoimmune inflammatory rheumatic diseasesConventional synthetic disease-modifying antirheumatic drugsClinical outcomes of COVID-19Outcomes of COVID-19Clinical outcomesInflammatory rheumatic diseasesAIRD patientsMeta-analysisSynthetic disease-modifying antirheumatic drugsRheumatic diseasesDisease-modifying antirheumatic drugsSusceptibility to COVID-19Case-control studySevere outcomes of COVID-19Increased susceptibility to COVID-19Antirheumatic drugsRelated deathsPatientsSteroidsDrug useGeneral populationCOVID-19 susceptibilitySystematic reviewNO effectCOVID-19
2021
Designing and validating a Markov model for hospital-based addiction consult service impact on 12-month drug and non-drug related mortality
King C, Englander H, Korthuis P, Barocas J, McConnell K, Morris C, Cook R. Designing and validating a Markov model for hospital-based addiction consult service impact on 12-month drug and non-drug related mortality. PLOS ONE 2021, 16: e0256793. PMID: 34506517, PMCID: PMC8432751, DOI: 10.1371/journal.pone.0256793.Peer-Reviewed Original ResearchConceptsAddiction consult serviceOpioid use disorderDrug-related deathsHospitalized patientsOUD careRelated mortalityPercent of patientsNon-drug related deathTrajectory of careSubstance use treatmentLogistic regression modelsACS careOUD treatmentPatient survivalRelated deathsSUD careConsult serviceMedicaid dataPatientsUse disordersMortalityUse treatmentCareBayesian logistic regression modelDeathPhysical activity and the risk of SARS-CoV-2 infection, severe COVID-19 illness and COVID-19 related mortality in South Korea: a nationwide cohort study
Lee S, Lee J, Moon S, Jin H, Yang J, Ogino S, Song M, Hong S, Ghayda R, Kronbichler A, Koyanagi A, Jacob L, Dragioti E, Smith L, Giovannucci E, Lee I, Lee D, Lee K, Shin Y, Kim S, Kim M, Won H, Ekelund U, Shin J, Yon D. Physical activity and the risk of SARS-CoV-2 infection, severe COVID-19 illness and COVID-19 related mortality in South Korea: a nationwide cohort study. British Journal Of Sports Medicine 2021, 56: 901-912. PMID: 34301715, DOI: 10.1136/bjsports-2021-104203.Peer-Reviewed Original ResearchConceptsMuscle strengthening activitiesPhysical activityCOVID-19 related deathsRisk of SARS-CoV-2 infectionGeneral health examinationCOVID-19 illnessStrengthening activitiesRecommended levels of physical activityHealth examinationLevels of physical activityNational Health Insurance Service of South KoreaPhysical activity guidelinesPhysical activity levelsMetabolic equivalent taskNational Health Insurance ServiceLikelihood of SARS-CoV-2 infectionRelated deathsNationwide cohort studyPublic health valueActivity guidelinesReduced risk of SARS-CoV-2 infectionEquivalent taskPatterns of associationKorean adultsSARS-CoV-2 positivity
2020
Updating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses
Wallach JD, Wang K, Zhang AD, Cheng D, Grossetta Nardini HK, Lin H, Bracken MB, Desai M, Krumholz HM, Ross JS. Updating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses. The BMJ 2020, 368: l7078. PMID: 32024657, PMCID: PMC7190063, DOI: 10.1136/bmj.l7078.Peer-Reviewed Original ResearchConceptsIndividual patient-level dataCardiovascular related deathsCardiovascular riskMyocardial infarctionRelated deathsSummary-level dataHeart failureOdds ratioSystematic reviewIncreased cardiovascular riskMore myocardial infarctionsHeart failure eventsCochrane Central RegistryAcute myocardial infarctionMyocardial infarction eventsPatient-level dataRandom-effects modelWeb of ScienceAnalysis of trialsEligible trialsComposite outcomeAdverse eventsContinuity correctionControlled TrialsRosiglitazone treatment
2018
Concomitant use of opioids and benzodiazepines in the outpatient setting: A retrospective study.
Simon J, Gehret J, Stolzenberg D, Beredjiklian P, Teng J, Paskey T, Raju R. Concomitant use of opioids and benzodiazepines in the outpatient setting: A retrospective study. PM&R 2018 PMID: 30243999, DOI: 10.1016/j.pmrj.2018.09.026.Peer-Reviewed Original ResearchPrescription drug monitoring programsOutpatient electronic medical recordsOutpatient settingConcomitant useNumber of opioidElectronic medical recordsOutpatient clinic visitsPatients Prescribed OpioidsAdministration of opioidsDrug monitoring programsClinic visitsMultiple providersCigarette/alcohol useBenzodiazepine prescriptionsOpioid related deathsRetrospective studyMedical recordsProvidersOpioidBenzodiazepinesPatientsRelated deathsPrescriptionMedicationPrescription(s
2011
Pre-eclampsia in low and middle income countries
Firoz T, Sanghvi H, Merialdi M, von Dadelszen P. Pre-eclampsia in low and middle income countries. Best Practice & Research Clinical Obstetrics & Gynaecology 2011, 25: 537-548. PMID: 21592865, DOI: 10.1016/j.bpobgyn.2011.04.002.Peer-Reviewed Original ResearchConceptsHealth care workersCare workersCommunity health care workersTreatment of eclampsiaDrug of choiceHealth care forcePerinatal morbidityBlood pressureMiddle-income countriesPre-eclampsiaExact prevalencePrinciples of careMaternal mortalityPregnant womenRelated deathsHealth care worker shortageTimely careEclampsiaPrevention strategiesLMICsLack of trainingMagnesium sulfateWomenIncome countriesMortality
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