Non-Hodgkin's Lymphoma, Phase II

A Multi-center Single Arm Phase II Study to Evaluate the Safety and Efficacy of Genetically Engineered Autologous Cells Expressing Anti-CD20 and Anti-CD19 Specific Chimeric Antigen Receptor in Subjects With Relapsed and/or Refractory Diffuse Large B Cell Lymphoma

Volunteers
Health Professionals

What is the purpose of this trial?

This is an open label, single arm, phase II study to determine the efficacy, safety and PK (persistence) of MBCART2019.1 cells in adults with relapsed or refractory DLBCL after receiving at least two lines of therapy.

Find out more about who can participate in this trial

Contact Information

For more information about this study, including how to volunteer, contact Iris Isufi

iris.isufi@yale.edu

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Principal Investigator

Iris Isufi, MD
Associate Professor of Medicine (Hematology); Co-Director Adult CAR T-Cell Therapy Program, Hematology; Co-Leader, Cellular Therapy Clinical Research Team, Yale Cancer Center; Co-Chair, Cellular Therapy (CT)-SAFE Committee, Yale Cancer Center

Sub-Investigators

Last Updated
10/10/2024
Study HIC
#2000028478