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Diseases of the Blood | Infectious Diseases, Phase III

Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS)

What is the purpose of this trial?

Brief Summary:

Multicenter, prospective, phase 3 randomized non-blinded interventional trial of fluid treatment strategies in the first 24 hours for patients with sepsis-induced hypotension. The aim of the study is to determine the impact of a restrictive fluids strategy (vasopressors first followed by rescue fluids) as compared to a liberal fluid strategy (fluids first followed by rescue vasopressors) on 90-day in-hospital mortality in patients with sepsis-induced hypotension.

  • Trial with
    Baystate Medical Center
  • Ages
    18 years and older
  • Gender
    Both

Contact Information

For more information about this study, including how to volunteer, contact Charles Wira

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  • Last Updated
    07/25/2024
  • Study HIC
    #2000023369