Colon, Phase II
A Phase 2 Trial to Evaluate the Safety and Efficacy of Combination Therapies in Patients With Advanced Upper Gastrointestinal Tract Malignancies (EDGE-Gastric)
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What is the purpose of this trial?
This is a Phase 2, open-label, parallel 3-cohort, multicenter study to evaluate the safety and preliminary clinical activity of treatment combinations with and without chemotherapy in participants with locally advanced unresectable or metastatic gastric, GEJ, and esophageal adenocarcinoma. Chemotherapy will consist of FOLFOX (oxaliplatin, leucovorin, fluorouracil).
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Principal Investigator
Sub-Investigators
- Andrea Brennan
- Ashita Talsania, MRCP, MBBS
- David Witt, MD
- Elan Gorshein, DO, JD, MPH
- Jacquelyne Gaddy, MD, MSc, MSCR
- Jeremy Kortmansky, MD
- Justin Persico, MD
- Karen Ann Hammond, DNP, APRN, ACNP (BC)
- Katelyn Scott
- Kert Sabbath, MD, FACP
- Kristen Hoxie
- Larisa Fleysher
- Laura Van Metre Baum, MD, MPH
- M. Sung Lee, MD
- Michael Cecchini, MD
- Michael Cohenuram, MD
- Michael Grant, MD
- Neal Fischbach, MD
- Pamela L. Kunz, MD
- Renee Moye
- Sarah Carlson
- Sarah Thomen, APRN
- Sharynn Hall, MD, PhD
- Stacey Stein, MD
- Su Hsien Lim, MD
- Teresa White
- Vanna Dest
- Victor Chang, MD
- Virginia Syombathy
- Last Updated10/03/2024
- Study HIC#2000033245