Single mechanically-gated cation channel currents can trigger action potentials in neocortical and hippocampal pyramidal neurons
Nikolaev Y, Dosen P, Laver D, van Helden D, Hamill O. Single mechanically-gated cation channel currents can trigger action potentials in neocortical and hippocampal pyramidal neurons. Brain Research 2015, 1608: 1-13. PMID: 25765154, DOI: 10.1016/j.brainres.2015.02.051.Peer-Reviewed Original ResearchConceptsHippocampal pyramidal neuronsPyramidal neuronsChannel currentsSpike activityAction potentialsRhythmic spike activityCell-attached patch recordingsTraumatic brain injuryCerebellar Purkinje neuronsMouse brain slicesCation channel currentsCentral neuronsBrain injuryLocus coeruleusBrain slicesSynaptic inputsVoltage-gated channelsPurkinje neuronsPatch recordingsInward currentsMammalian brainNeuron typesNeuronsMechanosensitive organCation channels