2018
Tuning ion channel mechanosensitivity by asymmetry of the transbilayer pressure profile
Martinac B, Bavi N, Ridone P, Nikolaev YA, Martinac AD, Nakayama Y, Rohde PR, Bavi O. Tuning ion channel mechanosensitivity by asymmetry of the transbilayer pressure profile. Biophysical Reviews 2018, 10: 1377-1384. PMID: 30182202, PMCID: PMC6233343, DOI: 10.1007/s12551-018-0450-3.Peer-Reviewed Original ResearchTransbilayer pressure profileMS channelsIon channel mechanosensitivityLipid bilayersMechanosensitive ion channelsSubmillisecond time scaleMembrane lipid environmentStructure-function relationshipsChannel mechanosensitivityMembrane proteinsDownstream effectorsLipid environmentIntracellular signalsCellular membranesConformational changesBiophysical principlesChannel reconstitutionIon channelsMechanical stimuliTime scalesPressure profileSpecific interactionsMechanical forcesCentral roleReconstitution method
2017
Principles of Mechanosensing at the Membrane Interface
Bavi N, Nikolaev Y, Bavi O, Ridone P, Martinac A, Nakayama Y, Cox C, Martinac B. Principles of Mechanosensing at the Membrane Interface. Springer Series In Biophysics 2017, 19: 85-119. DOI: 10.1007/978-981-10-6244-5_4.Peer-Reviewed Original ResearchChannel mechanosensitivityTransbilayer pressure profileIon channel mechanosensitivitySpecific cellular responsesMechanosensitive ion channelsMolecular mechanosensorsCellular mechanotransductionIntracellular signalsPhysiological processesCellular responsesMechanosensory transducersLiving cellsExtracellular matrixIon channelsChannel conformationLipid bilayersMembrane interfaceMechanotransductionMechanosensitivityMechanical stimuliCellsCytoskeletonMechanosensorsLipidsConformation