2015
Quantifying and Optimizing Single-Molecule Switching Nanoscopy at High Speeds
Lin Y, Long JJ, Huang F, Duim WC, Kirschbaum S, Zhang Y, Schroeder LK, Rebane AA, Velasco MG, Virrueta A, Moonan DW, Jiao J, Hernandez SY, Zhang Y, Bewersdorf J. Quantifying and Optimizing Single-Molecule Switching Nanoscopy at High Speeds. PLOS ONE 2015, 10: e0128135. PMID: 26011109, PMCID: PMC4444241, DOI: 10.1371/journal.pone.0128135.Peer-Reviewed Original Research
2012
Combined versatile high-resolution optical tweezers and single-molecule fluorescence microscopy
Sirinakis G, Ren Y, Gao Y, Xi Z, Zhang Y. Combined versatile high-resolution optical tweezers and single-molecule fluorescence microscopy. Review Of Scientific Instruments 2012, 83: 093708. PMID: 23020384, PMCID: PMC3465359, DOI: 10.1063/1.4752190.Peer-Reviewed Original ResearchMeSH KeywordsBacteriophage lambdaBase SequenceCarbocyaninesDNA, ViralInverted Repeat SequencesMicroscopy, FluorescenceOptical TweezersConceptsOptical tweezersSingle-molecule fluorescence microscopyDual-trap optical tweezersForce modeHigh-resolution optical tweezersConstant force modeSingle-molecule fluorescence detectionFluorescence microscopySingle-molecule approachOptical trappingDNA hairpin moleculesSingle-molecule fluorescenceSimilar microscopesSingle-molecule levelImaging configurationsΛ-DNA moleculesTweezersMolecular machinesDNA moleculesEasy data interpretationFluorescence signalHairpin moleculesSpatiotemporal resolutionMicroscopyComplementary oligonucleotides