2021
Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database
Cheng E, Blackburn HN, Ng K, Spiegelman D, Irwin ML, Ma X, Gross CP, Tabung FK, Giovannucci EL, Kunz PL, Llor X, Billingsley K, Meyerhardt JA, Ahuja N, Fuchs CS. Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database. JAMA Network Open 2021, 4: e2112539. PMID: 34132794, PMCID: PMC8209612, DOI: 10.1001/jamanetworkopen.2021.12539.Peer-Reviewed Original ResearchConceptsEarly-onset colorectal cancerOnset colorectal cancerNational Cancer DatabaseColorectal cancerAge 51Overall survivalCancer DatabaseIncidence of CRCCox proportional hazards regressionPrimary colorectal cancerKaplan-Meier analysisProportional hazards regressionAge 50 yearsAge 25 yearsAnalysis of survivalCohort studySurvival benefitHazards regressionUnadjusted analysesCancer incidenceMAIN OUTCOMEAge 35Survival advantageLower riskStage IPatterns of Care for Older Patients With Myelofibrosis: A Population-based Study
Meckstroth S, Wang R, Ma X, Podoltsev N. Patterns of Care for Older Patients With Myelofibrosis: A Population-based Study. Clinical Lymphoma Myeloma & Leukemia 2021, 21: e551-e558. PMID: 33648884, DOI: 10.1016/j.clml.2021.01.025.Peer-Reviewed Original ResearchConceptsPatterns of careOlder patientsEnd Results-Medicare databaseJAK inhibitor eraHigh-risk patientsPopulation-based studyUse of ruxolitinibJAK inhibitor ruxolitinibUnited States FoodRuxolitinib approvalMedian ageMedian timeTreatment patternsD claimsCurrent treatmentInhibitor ruxolitinibPatientsBetter outcomesClinical experienceDrug AdministrationMedicare Part BMyelofibrosisRuxolitinibStates FoodNew drugs
2020
Birth Characteristics and Risk of Pediatric Thyroid Cancer: A Population-Based Record-Linkage Study in California
Deziel N, Zhang Y, Wang R, Wiemels JL, Morimoto L, Clark CJ, Metayer C, Ma X. Birth Characteristics and Risk of Pediatric Thyroid Cancer: A Population-Based Record-Linkage Study in California. Thyroid 2020, 31: 596-606. PMID: 32912083, PMCID: PMC8195873, DOI: 10.1089/thy.2020.0217.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge of OnsetBirth CertificatesBirth OrderBirth WeightCaliforniaCase-Control StudiesChildChild, PreschoolEducational StatusFemaleHispanic or LatinoHumansIncidenceInfantInfant, NewbornMaleRace FactorsRegistriesRisk AssessmentRisk FactorsSex FactorsThyroid NeoplasmsTime FactorsYoung AdultConceptsPediatric thyroid cancerHigh birth weightFollicular thyroid cancerThyroid cancerHigher birth orderBirth characteristicsRisk factorsHispanic ethnicityBirth weightOdds ratioFirst primary thyroid cancerPapillary thyroid cancer casesBirth orderMultivariable logistic regression modelSecond primary malignanciesLong-term therapyAdjusted odds ratioPopulation-based studyPrimary thyroid cancerRecord linkage studyConfidence intervalsImportant risk factorCancer registry dataCase-control studyThyroid cancer cases
2016
Cesarean Section and Risk of Childhood Acute Lymphoblastic Leukemia in a Population-Based, Record-Linkage Study in California
Wang R, Wiemels JL, Metayer C, Morimoto L, Francis SS, Kadan-Lottick N, DeWan AT, Zhang Y, Ma X. Cesarean Section and Risk of Childhood Acute Lymphoblastic Leukemia in a Population-Based, Record-Linkage Study in California. American Journal Of Epidemiology 2016, 185: 96-105. PMID: 27986703, PMCID: PMC5253971, DOI: 10.1093/aje/kww153.Peer-Reviewed Original ResearchConceptsElective C-sectionAcute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaC-sectionCesarean sectionLymphoblastic leukemiaHigh riskPopulation-based case-control studyPeak ageEmergency C-sectionRecord linkage studyCancer registry dataCase-control studyPotential risk factorsEtiology of childhoodRelationship of modeVaginal deliveryRisk factorsRole of deliveryRegistry dataElevated riskBirth recordsInaccurate recallChildhoodRiskBirth weight and risk of paediatric Hodgkin lymphoma: Findings from a population-based record linkage study in California
Triebwasser C, Wang R, DeWan AT, Metayer C, Morimoto L, Wiemels JL, Kadan-Lottick N, Ma X. Birth weight and risk of paediatric Hodgkin lymphoma: Findings from a population-based record linkage study in California. European Journal Of Cancer 2016, 69: 19-27. PMID: 27814470, PMCID: PMC5125877, DOI: 10.1016/j.ejca.2016.09.016.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetBirth OrderBirth WeightCaliforniaCase-Control StudiesChildChild, PreschoolEthnicityFemaleFetal MacrosomiaHodgkin DiseaseHumansInfantInfant, Low Birth WeightInfant, NewbornInformation Storage and RetrievalLogistic ModelsMaleMaternal AgeOdds RatioPaternal AgeRisk FactorsConceptsAge of diagnosisPediatric Hodgkin lymphomaHigh birth weightBirth weightTime of deliveryHodgkin's lymphomaOdds ratioPopulation-based record linkage studyPopulation-based case-control studyBirth orderNormal birth weightRecord linkage studyCase-control studyConditional logistic regressionMagnitude of associationSubgroup of childrenPerinatal factorsMaternal ageEtiological investigationBirth recordsPaternal ageHL casesDisease riskLogistic regressionDiagnosis
2012
Patterns of subsequent malignancies after Hodgkin lymphoma in children and adults
Omer B, Kadan‐Lottick N, Roberts KB, Wang R, Demsky C, Kupfer GM, Cooper D, Seropian S, Ma X. Patterns of subsequent malignancies after Hodgkin lymphoma in children and adults. British Journal Of Haematology 2012, 158: 615-625. PMID: 22775513, DOI: 10.1111/j.1365-2141.2012.09211.x.Peer-Reviewed Original ResearchConceptsSecond malignant neoplasmsStandardized incidence ratiosSolid second malignant neoplasmsExtended field radiotherapyRecent treatment optionsLow-dose radiationSMN riskSubsequent malignanciesModality therapyIncidence ratiosHodgkin's lymphomaTreatment optionsMalignant neoplasmsSubgroup analysisCMT groupLower incidenceHigh riskGeneral populationAlkylator chemotherapyPatientsDose radiationRiskRadiotherapyChildrenAdults
2008
Infection and pediatric acute lymphoblastic leukemia
Ma X, Urayama K, Chang J, Wiemels JL, Buffler PA. Infection and pediatric acute lymphoblastic leukemia. Blood Cells Molecules And Diseases 2008, 42: 117-120. PMID: 19064328, PMCID: PMC2834409, DOI: 10.1016/j.bcmd.2008.10.006.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetCase-Control StudiesChildChild Day Care CentersChild, PreschoolClone CellsCocarcinogenesisEmploymentForecastingHumansInfantInfectionsModels, BiologicalMutationNorth CarolinaParentsPrecursor B-Cell Lymphoblastic Leukemia-LymphomaPrecursor Cell Lymphoblastic Leukemia-LymphomaProspective StudiesRisk FactorsVaccinationConceptsNorthern California Childhood Leukemia StudyVaccination historyPediatric acute lymphoblastic leukemiaAcute lymphoblastic leukemiaCalifornia Childhood Leukemia StudyChild's vaccination historyChildhood Leukemia StudyDaycare attendanceLymphoblastic leukemiaInfectious agentsImmune systemLeukemia StudyChildren's exposureInfectionRecent findingsExposureSocial contactLeukemia