2024
Collective dynamics of actin and microtubule and its crosstalk mediated by FHDC1
San Tong C, Su M, Sun H, Le Chua X, Xiong D, Guo S, Raj R, Ong N, Lee A, Miao Y, Wu M. Collective dynamics of actin and microtubule and its crosstalk mediated by FHDC1. Frontiers In Cell And Developmental Biology 2024, 11: 1261117. PMID: 38567385, PMCID: PMC10985548, DOI: 10.3389/fcell.2023.1261117.Peer-Reviewed Original ResearchActin wavesActin polymerizationFormin-mediated actin polymerizationDynamics of actinMultiple cellular processesActin nucleationCell cortexCytoskeletal networkCellular processesMicrotubule networkCell divisionMicrotubule depolymerizationActinAntagonistic interplayMicrotubulesMolecular insightsProtein 1CellsCdc42Mast cellsConcurrent releaseDepolymerizationInteractionInhibition
2023
Periodicity, mixed-mode oscillations, and multiple timescales in a phosphoinositide-Rho GTPase network
San Tong C, Xǔ X, Wu M. Periodicity, mixed-mode oscillations, and multiple timescales in a phosphoinositide-Rho GTPase network. Cell Reports 2023, 42: 112857. PMID: 37494180, DOI: 10.1016/j.celrep.2023.112857.Peer-Reviewed Original Research
2018
Membrane shape-mediated wave propagation of cortical protein dynamics
Wu Z, Su M, Tong C, Wu M, Liu J. Membrane shape-mediated wave propagation of cortical protein dynamics. Nature Communications 2018, 9: 136. PMID: 29321558, PMCID: PMC5762918, DOI: 10.1038/s41467-017-02469-1.Peer-Reviewed Original ResearchConceptsMembrane shape changesF-BAR proteinsDomain-containing proteinsPeripheral membrane proteinsProtein lateral diffusionActin machineryProtein recruitmentMembrane proteinsProtein dynamicsCortical proteinsShape changesProtein waveActin wavesUnderappreciated roleProteinMembrane undulationsLateral diffusionSpatial gradientsMachineryCytoplasmImmune cellsRecruitmentAssemblyCells
2017
Pulses and waves of contractility
Wu M. Pulses and waves of contractility. Journal Of Cell Biology 2017, 216: 3899-3901. PMID: 29138250, PMCID: PMC5716294, DOI: 10.1083/jcb.201710079.Peer-Reviewed Original ResearchProbing Mammalian Cell Size Homeostasis by Channel-Assisted Cell Reshaping
Varsano G, Wang Y, Wu M. Probing Mammalian Cell Size Homeostasis by Channel-Assisted Cell Reshaping. Cell Reports 2017, 20: 397-410. PMID: 28700941, DOI: 10.1016/j.celrep.2017.06.057.Peer-Reviewed Original ResearchConceptsCell size homeostasisSize homeostasisSize checkpointCell cycle progressionMammalian cell growthG1/SCell sizeCell reshapingMammalian cellsHomeostasis mechanismsCell growthRat basophilic leukemia cellsCell lengthBasophilic leukemia cellsCheckpointHomeostasisCell size measurementsLeukemia cellsAlternative mechanismCellsRAW 264.7 macrophages
2015
Shaping Developing Tissues with Light
Wu M. Shaping Developing Tissues with Light. Developmental Cell 2015, 35: 533-534. PMID: 26651289, DOI: 10.1016/j.devcel.2015.11.020.Peer-Reviewed Original Research
2013
Calcium oscillations-coupled conversion of actin travelling waves to standing oscillations
Wu M, Wu X, De Camilli P. Calcium oscillations-coupled conversion of actin travelling waves to standing oscillations. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 1339-1344. PMID: 23297209, PMCID: PMC3557052, DOI: 10.1073/pnas.1221538110.Peer-Reviewed Original ResearchConceptsPlasma membraneActin regulatory proteinsActin cytoskeletonActin dynamicsActive Cdc42Cell cortexCell physiologyRegulatory proteinsActin polymerizationDynamic spatial patternsMacromolecular assembliesCalcium oscillationsSpatial patternsActinMembraneFBP17Cdc42CellsCytoskeletonFeedback mechanismProteinPhysiologyAntigen stimulationGlobal fluctuationsMechanism
2012
Chapter 1 Supported Native Plasma Membranes as Platforms for the Reconstitution and Visualization of Endocytic Membrane Budding
Wu M, De Camilli P. Chapter 1 Supported Native Plasma Membranes as Platforms for the Reconstitution and Visualization of Endocytic Membrane Budding. Methods In Cell Biology 2012, 108: 1-18. PMID: 22325595, DOI: 10.1016/b978-0-12-386487-1.00001-8.Peer-Reviewed Original ResearchConceptsPlasma membranePlasma membrane sheetsNative plasma membraneEndocytic budsCell-free assayMembrane buddingEndocytic eventsMolecular dissectionElucidation of mechanismsCytosolic extractsBiological membranesMembrane sheetsEndocytosisExtracellular materialRobust formationMembraneSubsequent incubationVariety of manipulationsReconstitutionCellsExperimental systemPowerful toolFissionBuddingBuds
2008
Nanobiotechnology and Cell Biology: Micro- and Nanofabricated Surfaces to Investigate Receptor-Mediated Signaling
Torres AJ, Wu M, Holowka D, Baird B. Nanobiotechnology and Cell Biology: Micro- and Nanofabricated Surfaces to Investigate Receptor-Mediated Signaling. Annual Review Of Biophysics 2008, 37: 265-288. PMID: 18573082, DOI: 10.1146/annurev.biophys.36.040306.132651.Peer-Reviewed Original ResearchConceptsCell biologySpatial regulationReceptor-mediated signalingCellular processesChemical modification schemesCellular interactionsFluorescence microscopyBiologySignalingCellsRegulationFundamental mechanismsReceptor systemImmune cellsNew informationEngineering toolsReceptorsPhysical environmentNew opportunities
2007
Differential targeting of secretory lysosomes and recycling endosomes in mast cells revealed by patterned antigen arrays
Wu M, Baumgart T, Hammond S, Holowka D, Baird B. Differential targeting of secretory lysosomes and recycling endosomes in mast cells revealed by patterned antigen arrays. Journal Of Cell Science 2007, 120: 3147-3154. PMID: 17698921, DOI: 10.1242/jcs.007260.Peer-Reviewed Original Research