Vincent Quagliarello, MD
Professor of Medicine (Infectious Diseases)Cards
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Clinical Chief, Infectious Diseases
Vice Chair for Education and Academic Affairs, Department of Internal Medicine
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Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Clinical Chief, Infectious Diseases
Vice Chair for Education and Academic Affairs, Department of Internal Medicine
Contact Info
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Clinical Chief, Infectious Diseases
Vice Chair for Education and Academic Affairs, Department of Internal Medicine
Contact Info
About
Titles
Professor of Medicine (Infectious Diseases)
Clinical Chief, Infectious Diseases; Vice Chair for Education and Academic Affairs, Department of Internal Medicine
Biography
Dr. Quagliarello received his undergraduate degree from Johns Hopkins University and his M.D. from Washington University in St. Louis prior to training as an intern, resident and Chief Resident in Internal Medicine at Yale. After completing a fellowship in Infectious Diseases at University of Virginia, he returned to Yale where he is currently Professor of Medicine, Clinical Chief of Infectious Diseases, and Vice Chair for Education and Academic Affairs. During his time on the Yale faculty, Dr. Quagliarello has served as an educational leader in directing the Internal Medicine Clerkship, the Yale Infectious Diseases Fellowship program, and he created and directs the Department of Medicine Research in Residency Program. He has complimented his clinical and educational work with his expertise as a nationally recognized investigator in the pathophysiology and management of meningitis, and the prognostic classification and management of endocarditis. For the past several years, his scholarship has focused on infections among older adults as an NIH R01 funded principal investigator and a recipient of an NIH K07 Academic Leadership Award to mentor trainees at the postdoctoral and junior faculty level to develop interdisciplinary research at the interface of Infectious Diseases and Geriatrics. Dr. Quagliarello has been an award winning educator having received the Yale Internal Medicine Teacher of the Year award (twice), the Alice Bohmfalk Teaching Prize and the Leah Lowenstein Award from Yale School of Medicine, the Laureate Award from the American College of Physicians (CT Chapter) and the Clinical Teacher Award at the national meeting of the Infectious Diseases Society of America.
Appointments
Infectious Diseases
ProfessorPrimary
Other Departments & Organizations
Education & Training
- Fellow
- University of Virginia (1987)
- Resident
- Yale-New Haven Hospital (1984)
- MD
- Washington University (1980)
Research
Overview
Medical Research Interests
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Manisha Juthani, MD
Rupak Datta, MD/PhD, MPH
Mary Tinetti, MD
Heather Allore, PhD
Andrea Rink
Ling Han, MD, PhD, MS
Nursing Homes
Pneumonia
Meningitis
Endocarditis
Publications
2024
Cohort study of patients with advanced cancer: outcomes associated with duration of antibiotic therapy for non-ventilator hospital-acquired pneumonia
Lee S, Benson J, Cohen A, Quagliarello V, Juthani-Mehta M, Datta R. Cohort study of patients with advanced cancer: outcomes associated with duration of antibiotic therapy for non-ventilator hospital-acquired pneumonia. Antimicrobial Stewardship & Healthcare Epidemiology 2024, 4: e48. PMID: 38655023, PMCID: PMC11036428, DOI: 10.1017/ash.2024.54.Peer-Reviewed Original ResearchAltmetricConceptsNon-ventilator hospital-acquired pneumoniaAdvanced cancerPalliative care settingHospital-acquired pneumoniaCohort study of patientsCare settingsOlder adultsAdjusted oddsDuration of antibiotic therapyAssociated with reduced adjusted oddsSingle-center observational studyCohort studyProlonged antibiotic durationObservational studyStudy of patientsAntimicrobial stewardship effortsAntibiotic durationAntibiotic therapyStewardship effortsPneumoniaCancerOddsReadmissionAdultsCohort
2023
Antibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study
Datta R, Han L, Doyle M, Allore H, Sanft T, Quagliarello V, Juthani-Mehta M. Antibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study. Palliative Medicine 2023, 37: 793-798. PMID: 36999898, DOI: 10.1177/02692163231162889.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAdverse drug eventsAntibiotic therapyDrug eventsAdvanced cancerOlder adultsIndex admissionPalliative chemotherapyCohort studyTertiary care centerHospitalized older adultsPalliative care providersMultidrug-resistant organismsMean ageCommon tumorsCare centerCare providersRatio of daysSolid tumorsMultivariable testingPatientsTherapyStandardized criteriaCancerMean timeAdults
2022
Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancer
Lee S, O’Donovan L, Cohen A, Gautam S, Quagliarello V, Juthani-Mehta M, Datta R. Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancer. Antimicrobial Stewardship & Healthcare Epidemiology 2022, 2: e152. PMID: 36483405, PMCID: PMC9726473, DOI: 10.1017/ash.2022.293.Peer-Reviewed Original ResearchCitationsAltmetric
2020
Education needed to improve antimicrobial use during end-of-life care of older adults with advanced cancer: A cross-sectional survey
Datta R, Topal J, McManus D, Sanft T, Dembry LM, Morrison LJ, Quagliarello V, Juthani-Mehta M. Education needed to improve antimicrobial use during end-of-life care of older adults with advanced cancer: A cross-sectional survey. Palliative Medicine 2020, 35: 236-241. PMID: 32928066, DOI: 10.1177/0269216320956811.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsEscalation of careAdvance care planningLife careAdvanced cancerCross-sectional surveyIntravenous antimicrobialsOlder adultsAntimicrobial useCare planningSingle-center cross-sectional surveyEducational interventionAdvance care plansRole of antimicrobialsClinical deteriorationPercent of respondentsAdverse eventsOral antimicrobialsMedicine subspecialistsCare plansInpatient medicineCareCancerPatientsAdultsSubspecialists
2019
Perspectives on antimicrobial use at the end of life among antibiotic stewardship programs: A survey of the Society for Healthcare Epidemiology of America Research Network
Datta R, Topal J, McManus D, Dembry LM, Quagliarello V, Juthani-Mehta M. Perspectives on antimicrobial use at the end of life among antibiotic stewardship programs: A survey of the Society for Healthcare Epidemiology of America Research Network. Infection Control And Hospital Epidemiology 2019, 40: 1074-1076. PMID: 31328703, PMCID: PMC7165360, DOI: 10.1017/ice.2019.194.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsIncreased Length of Stay Associated With Antibiotic Use in Older Adults With Advanced Cancer Transitioned to Comfort Measures
Datta R, Zhu M, Han L, Allore H, Quagliarello V, Juthani-Mehta M. Increased Length of Stay Associated With Antibiotic Use in Older Adults With Advanced Cancer Transitioned to Comfort Measures. American Journal Of Hospice And Palliative Medicine® 2019, 37: 27-33. PMID: 31185722, PMCID: PMC6868290, DOI: 10.1177/1049909119855617.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAdvanced cancerAntibiotic useComfort measuresPoisson regression modelsInfection diagnosisIntensive care unit admissionMultivariable Poisson regression modelsCare unit admissionCohort of patientsUrinary tract infectionGoal-concordant careUnit admissionEnd of lifeHospital lengthOlder patientsTract infectionsLonger LOSMedian ageRegression modelsStay AssociatedAntibiotic exposureLiquid tumorsPatientsCancerCancer typesAntimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures
Datta R, Wang T, Zhu M, Dembry LM, Han L, Allore H, Quagliarello V, Juthani-Mehta M. Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures. Infection Control And Hospital Epidemiology 2019, 40: 470-472. PMID: 30821230, PMCID: PMC6482377, DOI: 10.1017/ice.2019.22.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsUrinary tract infectionIncidence rate ratiosAdvanced cancer patientsAsymptomatic bacteriuriaCancer patientsAntimicrobial therapySymptomatic urinary tract infectionPotential urinary tract infectionTract infectionsInappropriate therapyAntimicrobial daysComfort measuresBacteriuriaCandiduriaCFU/mLPatientsTherapyRate ratioMLInfection
2018
Increased Fluoroquinolone-Susceptibility and Preserved Nitrofurantoin-Susceptibility among Escherichia coli Urine Isolates from Women Long-Term Care Residents: A Brief Report
Datta R, Advani S, Rink A, Bianco L, Van Ness PH, Quagliarello V, Juthani-Mehta M. Increased Fluoroquinolone-Susceptibility and Preserved Nitrofurantoin-Susceptibility among Escherichia coli Urine Isolates from Women Long-Term Care Residents: A Brief Report. Open Access Journal Of Gerontology & Geriatric Medicine 2018, 4: 555636. PMID: 30465048, PMCID: PMC6241532, DOI: 10.19080/oajggm.2018.04.555636.Peer-Reviewed Original ResearchCitationsAltmetricConceptsLong-term care residentsUrinary tract infectionUrine isolatesCare residentsTract infectionsUncomplicated urinary tract infectionsLong-term care facilitiesTrimethoprim/sulfamethoxazoleEmpiric therapyCommon indicationOptimal therapyUrine cultureUrinary isolatesAntimicrobial therapyClinical trialsNitrofurantoin susceptibilityCare facilitiesFluoroquinolone susceptibilityAntimicrobial susceptibilityPredominant organismTherapyInfectionCefazolinIsolatesBacterial isolatesFrequency of Infection during Fever Episodes among Long-Term Care Residents
Datta R, Advani S, Rink A, Bianco L, Van Ness PH, Quagliarello V, Juthani-Mehta M. Frequency of Infection during Fever Episodes among Long-Term Care Residents. Journal Of Gerontology & Geriatric Research 2018, 7: 1-2. PMID: 30197840, PMCID: PMC6128293, DOI: 10.4172/2167-7182.1000467.Peer-Reviewed Original ResearchCitationsAltmetricConceptsLong-term care residentsLong-term care facilitiesFever episodesFrequency of infectionCare residentsCare facilitiesCase series analysisAdverse event surveillanceOlder adult womenCranberry capsulesMedian ageRandomized trialsSurveillance definitionsProvider assessmentTotal infectionsAdult womenInfectionOlder adultsEvent surveillanceWomenEpisodesTwo-thirdsResidentsPyuriaBacteriuria
2017
Serious adverse events of older adults in nursing home and community intervention trials
Datta R, Trentalange M, Van Ness PH, McGloin JM, Guralnik JM, Miller ME, Walkup MP, Nadkarni N, Pahor M, Gill TM, Quagliarello V, Juthani-Mehta M, Group F. Serious adverse events of older adults in nursing home and community intervention trials. Contemporary Clinical Trials Communications 2017, 9: 77-80. PMID: 29696228, PMCID: PMC5898490, DOI: 10.1016/j.conctc.2017.12.004.Peer-Reviewed Original ResearchCitationsAltmetricConceptsUnanticipated serious adverse eventsSerious adverse eventsNursing home residentsTotal serious adverse eventsHome residentsSAE incidenceAdverse eventsClinical trialsOlder adultsCommunity dwellersNursing homesIncidence of SAEsFemale nursing home residentsProportion of patientsRandomized clinical trialsCommunity intervention trialStructured physical activityCranberry capsulesLifestyle interventionRandomized trialsIntervention trialsElders StudyHealth centersSecondary data analysisPhysical activity
Academic Achievements & Community Involvement
honor Clinical Teacher Award
National AwardInfectious Diseases Society of AmericaDetails10/20/2011United Stateshonor Leah Lowenstein Award
Yale School of Medicine AwardYale University School of MedicineDetails05/31/2007United Stateshonor Department of Internal Medicine Teacher of the Year
Yale School of Medicine AwardYale University School of Medicine Department of Internal MedicineDetails06/30/1998, 06/30/1990United Stateshonor Laureate Award
Regional AwardAmerican College of Physicians (Connecticut Chapter)Details10/31/1997United Stateshonor Bohmfalk Teaching Prize
Yale School of Medicine AwardYale University School of MedicineDetails05/26/1997United States
Clinical Care
Overview
Vincent Quagliarello, MD, is the vice chair for education and academic affairs for the Department of Internal Medicine and the clinical chief of Infectious Diseases at Yale Medicine. He enjoys treating a diversity of illnesses that have a direct impact on public health.
“I enjoy evaluating patients at the bedside, mentoring trainees and colleagues, and writing,” he says.
In addition to his work as a clinician and educator, Dr. Quagliarello is a nationally recognized investigator in the pathophysiology and management of meningitis, and the prognostic classification and management of endocarditis (an infection of the heart’s inner linings).
For the past several years, he has focused on infections among older adults.
Dr. Quagliarello has twice received the Yale Internal Medicine Teacher of the Year Award, the Alice Bohmfalk Teaching Prize, and the Leah Lowenstein Award from Yale School of Medicine, the Laureate Award from the American College of Physicians (CT Chapter), and the Clinical Teacher Award at the national meeting of the Infectious Diseases Society of America.
Clinical Specialties
Board Certifications
Infectious Disease
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 1988
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 1984
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileNews
News
- May 14, 2024
Celebrating Health Profession Students' Poetry, Prose, and Visual Arts
- May 14, 2024
Research in Residency Day is May 16
- March 15, 2024
Announcing the New Residents in the Internal Medicine Primary Care Residency Program!
- March 15, 2024
Announcing the New Residents in the Yale-Waterbury Internal Medicine Residency Program!
Get In Touch
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Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.