2021
A Practical Clinical Approach to the Management of High-Risk Ulcerative Colitis.
Rubin D, Traboulsi C, Rai V. A Practical Clinical Approach to the Management of High-Risk Ulcerative Colitis. Gastroenterology & Hepatology 2021, 17: 59-66. PMID: 34035764, PMCID: PMC8132723.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsUlcerative colitisDisease activityRecurrent disease activityLong-term remissionManagement of patientsGoal of treatmentPractical clinical approachPatient's risk levelRange of symptomsAbdominal painRectal bleedingFulminant diseasePrognostic factorsSurgical optionsTherapeutic choiceInpatient settingPatientsClinical approachDrug mechanismsDisease responseRemissionColitisTreatmentObjective measuresCritical appraisalAssessment of Comorbid Depression and Anxiety in Inflammatory Bowel Disease Using Adaptive Testing Technology
Karpin J, Rodriguez T, Traboulsi C, Rai V, Gibbons R, Rubin D. Assessment of Comorbid Depression and Anxiety in Inflammatory Bowel Disease Using Adaptive Testing Technology. Crohn's & Colitis 360 2021, 3: otaa095. PMID: 34746788, PMCID: PMC8570563, DOI: 10.1093/crocol/otaa095.Peer-Reviewed Original ResearchInflammatory bowel diseaseBowel diseaseExact testActive inflammatory bowel diseaseClinical remission statusNegative CRP valuesMental health screeningPearson's chi-square testFisher's exact testMental health conditionsChi-square testCAT-MHIBD clinicIBD patientsPositive CRPUndiagnosed anxietyClinical remissionDisease activityIBD populationPatient characteristicsConsecutive patientsCRP valuesMultivariable analysisSignificant positive associationRemission status
2020
Effectiveness of Ustekinumab Dose Escalation in Patients With Crohn’s Disease
Ollech J, Normatov I, Peleg N, Wang J, Patel S, Rai V, Yi Y, Singer J, Dalal S, Sakuraba A, Cohen R, Rubin D, Pekow J. Effectiveness of Ustekinumab Dose Escalation in Patients With Crohn’s Disease. Clinical Gastroenterology And Hepatology 2020, 19: 104-110. PMID: 32109634, PMCID: PMC8665415, DOI: 10.1016/j.cgh.2020.02.035.Peer-Reviewed Original ResearchConceptsC-reactive proteinCrohn's diseaseFecal calprotectinInterval shorteningDisease activityStandard doseDose intervalMedian levelsLevels of CRPHarvey-Bradshaw Index scoreUstekinumab dose escalationSubset of patientsEndoscopic remissionClinical remissionEndoscopic evidenceDose escalationSingle centerRetrospective studyPatientsCalprotectinIndex scoreAbstractTextNormal levelsDiseaseWeeks
2019
Follow-Up of Patients With Ulcerative Colitis and Histological Normalization
Israel A, Christensen B, El Jurdi K, Rai V, Ollech J, Cohen R, Sakuraba A, Dalal S, Rubin D. Follow-Up of Patients With Ulcerative Colitis and Histological Normalization. Clinical Gastroenterology And Hepatology 2019, 18: 987-988.e1. PMID: 31228567, PMCID: PMC6923607, DOI: 10.1016/j.cgh.2019.06.025.Peer-Reviewed Original ResearchConceptsUlcerative colitisManagement of UCSpecific treatment goalsEndoscopic improvementHistological normalizationDisease activityMucosal injuryRemitting courseHistological endpointsTreatment goalsNatural historyColitisMicroscopic featuresUnanswered questionsInflammationPatientsChronicityMucosaInjuryHistologyDiagnosisEndpoint