2024
Patients with ulcerative colitis who have normalized histology are clinically stable after de-escalation of therapy
Akiyama S, St-Pierre J, Traboulsi C, Silfen A, Rai V, Rodriguez T, Erondu A, Steinberg J, Shaffer S, Christensen B, Rubin D. Patients with ulcerative colitis who have normalized histology are clinically stable after de-escalation of therapy. Npj Gut And Liver 2024, 1: 5. DOI: 10.1038/s44355-024-00005-9.Peer-Reviewed Original ResearchHistologic normalizationUlcerative colitisDe-escalationUC patientsDe-escalation of therapyTherapeutic de-escalationMedian follow-upDe-escalation groupProportion of patientsStudy assessed outcomesHistological recurrenceRecurrence rateSingle-centerClinical stabilityTherapeutic changeRemission outcomesFollow-upTherapyPatientsImmunomodulationAminosalicylatesWithdrawalColitisMonthsOutcomes
2021
A Practical Clinical Approach to the Management of High-Risk Ulcerative Colitis.
Rubin D, Traboulsi C, Rai V. A Practical Clinical Approach to the Management of High-Risk Ulcerative Colitis. Gastroenterology & Hepatology 2021, 17: 59-66. PMID: 34035764, PMCID: PMC8132723.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsUlcerative colitisDisease activityRecurrent disease activityLong-term remissionManagement of patientsGoal of treatmentPractical clinical approachPatient's risk levelRange of symptomsAbdominal painRectal bleedingFulminant diseasePrognostic factorsSurgical optionsTherapeutic choiceInpatient settingPatientsClinical approachDrug mechanismsDisease responseRemissionColitisTreatmentObjective measuresCritical appraisal
2020
Management of Patients With Crohn’s Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting
Rubin D, Abreu M, Rai V, Siegel C, Disease I, Ahuja V, Allez M, Ananthakrishnan A, Bernstein C, Braun J, Chowers Y, Colombel J, Danese S, D'Haens G, D'Hoore A, Dignass A, Dotan I, Dubinsky M, Ekbom A, Fleshner P, Gassull M, Gearry R, Ghosh S, Griffiths A, Halfvarson J, Hanauer S, Harpaz N, Hart A, Kamm M, Kaplan G, Koutroubakis I, Lakatos P, Levine A, Lewis J, Lindsay J, Loftus E, Louis E, Lukas M, Magro F, Mahadevan U, Mantzaris G, McGovern D, Moum B, Munkholm P, Neurath M, Ng S, O'Morain C, Panaccione R, Panes J, Peyrin-Biroulet L, Prantera C, Ran Z, Reinisch W, Remzi F, Sachar D, Sandborn W, Sartor R, Schölmerich J, Schreiber S, Siegmund B, Silverberg M, Söderholm J, Stange E, Steinwurz F, Turner D, Vatn M, Vermeire S, Brenner E, Christensen B, D'Amico F, Griffiths C, Higgins P, Kappelman M, Lees C, Regueiro M, Rosh J, Ungaro R. Management of Patients With Crohn’s Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting. Gastroenterology 2020, 159: 6-13.e6. PMID: 32272113, PMCID: PMC7194599, DOI: 10.1053/j.gastro.2020.04.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsRe: 18F-FDG PET-MR enterography in predicting histological active disease using the Nancy index in ulcerative colitis: a randomized controlled trial
Akiyama S, Traboulsi C, Rai V, Rubin D. Re: 18F-FDG PET-MR enterography in predicting histological active disease using the Nancy index in ulcerative colitis: a randomized controlled trial. European Journal Of Nuclear Medicine And Molecular Imaging 2020, 47: 2247-2247. PMID: 32242252, DOI: 10.1007/s00259-020-04774-2.Commentaries, Editorials and Letters
2019
Follow-Up of Patients With Ulcerative Colitis and Histological Normalization
Israel A, Christensen B, El Jurdi K, Rai V, Ollech J, Cohen R, Sakuraba A, Dalal S, Rubin D. Follow-Up of Patients With Ulcerative Colitis and Histological Normalization. Clinical Gastroenterology And Hepatology 2019, 18: 987-988.e1. PMID: 31228567, PMCID: PMC6923607, DOI: 10.1016/j.cgh.2019.06.025.Peer-Reviewed Original ResearchConceptsUlcerative colitisManagement of UCSpecific treatment goalsEndoscopic improvementHistological normalizationDisease activityMucosal injuryRemitting courseHistological endpointsTreatment goalsNatural historyColitisMicroscopic featuresUnanswered questionsInflammationPatientsChronicityMucosaInjuryHistologyDiagnosisEndpoint