2024
State paid family leave policies and breastfeeding duration: cross-sectional analysis of 2021 national immunization survey-child
Rosenberg J, Nardella D, Shabanova V. State paid family leave policies and breastfeeding duration: cross-sectional analysis of 2021 national immunization survey-child. International Breastfeeding Journal 2024, 19: 37. PMID: 38796467, PMCID: PMC11128124, DOI: 10.1186/s13006-024-00646-9.Peer-Reviewed Original ResearchConceptsFamily leaveParental leave policiesLeave policiesSocial demographic characteristicsPolicyCross-sectional analysisUnited StatesNational Immunization Survey-ChildMedical leaveFamilyBreastfeeding ratesPromote breastfeedingSurveyed childrenStateBreastfeedingWorkforceLong-term health benefitsNationalBreastfeeding durationMixed feedPrevalence ratios
2023
Diabetes in Pregnancy, Neonatal Morbidities, and Early Growth in Moderate or Late Preterm Infants.
Buck C, Shabanova V, Clark R, Taylor S. Diabetes in Pregnancy, Neonatal Morbidities, and Early Growth in Moderate or Late Preterm Infants. Pediatrics 2023, 152 PMID: 37969002, DOI: 10.1542/peds.2023-061285.Peer-Reviewed Original ResearchConceptsLate preterm infantsPreterm infantsGestational ageNeonatal morbidityBirth weightDay 14Pediatrix Clinical Data WarehouseNeonatal intensive care unitCommon neonatal morbiditiesShort-term morbidityIntensive care unitFirst postnatal dayPercent weight changeFirst postnatal weekClinical data warehouseDM groupRespiratory supportTerm morbidityCare unitDiabetes exposureAdjusted differenceCongenital anomaliesPostnatal dayHealth characteristicsPostnatal weekPediatricians' Reports of Interaction with Infant Formula Companies
Werner K, Mercurio M, Shabanova V, Hull S, Taylor S. Pediatricians' Reports of Interaction with Infant Formula Companies. Breastfeeding Medicine 2023, 18: 219-225. PMID: 36795978, DOI: 10.1089/bfm.2022.0217.Peer-Reviewed Original ResearchConceptsInfant formula companiesPercent of mothersRepresentative visitsMarketing Breast Milk SubstitutesAdvice of pediatriciansFormula companiesFree formula samplesWorld Health Organization International CodeHigh-income patientsBreast-milk substitutesHealth care staffHealth care facilitiesBreastfeeding practicesBehavior of mothersU.S. pediatriciansCare facilitiesCare staffDemographic dataPractice demographicsPediatriciansMilk substitutePrivate practiceZip codesPediatricians reportElectronic survey
2021
Age-Dependent Heterogeneity in the Efficacy of Prophylaxis With Enoxaparin Against Catheter-Associated Thrombosis in Critically Ill Children: A Post Hoc Analysis of a Bayesian Phase 2b Randomized Clinical Trial.
Faustino EVS, Raffini LJ, Hanson SJ, Cholette JM, Pinto MG, Li S, Kandil SB, Nellis ME, Shabanova V, Silva CT, Tala JA, McPartland T, Spinella PC. Age-Dependent Heterogeneity in the Efficacy of Prophylaxis With Enoxaparin Against Catheter-Associated Thrombosis in Critically Ill Children: A Post Hoc Analysis of a Bayesian Phase 2b Randomized Clinical Trial. Critical Care Medicine 2021, 49: e369-e380. PMID: 33566465, PMCID: PMC7979442, DOI: 10.1097/ccm.0000000000004848.Peer-Reviewed Original ResearchConceptsCentral venous catheter-associated deep venous thrombosisCatheter-associated deep venous thrombosisCentral venous cathetersEfficacy of prophylaxisDeep venous thrombosisAge-dependent heterogeneityAnti-Xa levelsVenous cathetersVenous thrombosisFactor VIII activityThrombin generationPlatelet countClinical trialsIll childrenPhase 2bVIII activityLow factor VIII activityCatheter-Associated ThrombosisInternational units/mLMinimum platelet countOlder childrenCritically Ill ChildrenEndogenous thrombin potentialHigher platelet countsPost Hoc Analysis
2020
Patterns of medication use at end of life by pediatric inpatients with cancer
Prozora S, Shabanova V, Ananth P, Pashankar F, Kupfer GM, Massaro SA, Davidoff AJ. Patterns of medication use at end of life by pediatric inpatients with cancer. Pediatric Blood & Cancer 2020, 68: e28837. PMID: 33306281, DOI: 10.1002/pbc.28837.Peer-Reviewed Original ResearchConceptsMedication usePediatric inpatientsVizient Clinical Database/Resource ManagerHematopoietic stem cell transplantLife-sustaining medicationsMedication utilization patternsSymptom management medicationsUse of opioidsStem cell transplantIntensive care unitLength of stayAcademic medical centerResource use dataLast weekWarrants further studyEvidence-based approachVasopressor useEnd of lifeCare unitCell transplantMedication categoriesResuscitate statusRetrospective studyMalignancy typeOdds ratioNon–FDA-Reviewed Imported European Formula Use Among Parents in Urban Pediatric Private Practice
Du N, DiMaggio DM, Williams JK, Leus I, Shabanova V, Song X, Porto AF. Non–FDA-Reviewed Imported European Formula Use Among Parents in Urban Pediatric Private Practice. Clinical Pediatrics 2020, 59: 566-572. PMID: 32146831, DOI: 10.1177/0009922820910819.Peer-Reviewed Original Research
2019
Parenteral Antibiotic Therapy Duration in Young Infants With Bacteremic Urinary Tract Infections
Desai S, Aronson PL, Shabanova V, Neuman MI, Balamuth F, Pruitt CM, DePorre AG, Nigrovic LE, Rooholamini SN, Wang ME, Marble RD, Williams DJ, Sartori L, Leazer RC, Mitchell C, Shah SS. Parenteral Antibiotic Therapy Duration in Young Infants With Bacteremic Urinary Tract Infections. Pediatrics 2019, 144: e20183844. PMID: 31431480, PMCID: PMC6855812, DOI: 10.1542/peds.2018-3844.Peer-Reviewed Original ResearchConceptsBacteremic urinary tract infectionUrinary tract infectionAntibiotic durationParenteral antibioticsTract infectionsFrequent recurrent urinary tract infectionsYoung infantsMulticenter retrospective cohort studyRecurrent urinary tract infectionsAntibiotic therapy durationShort-course groupRetrospective cohort studyLong-course therapyMarginal structural modelsHospital reutilizationUTI recurrenceOral antibioticsCohort studyParenteral therapyPatient characteristicsTherapy durationUrine cultureChildren's HospitalWeighted populationEarly conversionA Prediction Model to Identify Febrile Infants ≤60 Days at Low Risk of Invasive Bacterial Infection
Aronson PL, Shabanova V, Shapiro ED, Wang ME, Nigrovic LE, Pruitt CM, DePorre AG, Leazer RC, Desai S, Sartori LF, Marble RD, Rooholamini SN, McCulloh RJ, Woll C, Balamuth F, Alpern ER, Shah SS, Williams DJ, Browning WL, Shah N, Neuman MI. A Prediction Model to Identify Febrile Infants ≤60 Days at Low Risk of Invasive Bacterial Infection. Pediatrics 2019, 144: e20183604. PMID: 31167938, PMCID: PMC6615531, DOI: 10.1542/peds.2018-3604.Peer-Reviewed Original ResearchConceptsInvasive bacterial infectionsAbsolute neutrophil countFebrile infantsControl patientsNeutrophil countUrinalysis resultsBacterial infectionsAbnormal urinalysis resultsNormal urinalysis resultsComplex chronic conditionsCase-control studyMultiple logistic regressionDate of visitEmergency departmentChronic conditionsCerebrospinal fluidLower riskInfantsLogistic regressionPatientsHospitalScoresInfectionDaysLow probabilityAngiopoietin Level Trajectories in Toddlers With Severe Sepsis and Septic Shock and Their Effect on Capillary Endothelium
Pierce RW, Shabanova V, Canarie M, Pinto M, da Silva YS, Bhandari V, Giuliano JS. Angiopoietin Level Trajectories in Toddlers With Severe Sepsis and Septic Shock and Their Effect on Capillary Endothelium. Shock 2019, 51: 298-305. PMID: 30286031, PMCID: PMC6375782, DOI: 10.1097/shk.0000000000001172.Peer-Reviewed Original ResearchConceptsSevere sepsis/septic shockSepsis/septic shockTumor necrosis factorHuman dermal microvascular endothelial cellsCultured human dermal microvascular endothelial cellsSIRS/sepsisSeptic shockAngpt-1Severe sepsisAngpt-2Diagnostic biomarkersSevere sepsis/shockTertiary care pediatric hospitalEndothelial cellsAngpt-2 levelsOlder childrenSepsis/shockInflammatory response syndromeProspective observational studyTransendothelial electrical resistance measurementsDermal microvascular endothelial cellsAppropriate diagnostic biomarkersMicrovascular endothelial cellsYoung childrenEnzyme-linked immunoassayImpact of a dedicated nursing team on central line-related complications in neonatal intensive care unit
Levit O, Shabanova V, Bizzarro M. Impact of a dedicated nursing team on central line-related complications in neonatal intensive care unit. The Journal Of Maternal-Fetal & Neonatal Medicine 2019, 33: 2618-2622. PMID: 30612486, DOI: 10.1080/14767058.2018.1555814.Peer-Reviewed Original ResearchConceptsLine-related complicationsCentral line-related complicationsDedicated nursing teamCentral line insertionNursing teamLine insertionProspective observational cohort studyNeonatal intensive care unitCatheter-related complicationsObservational cohort studyIntensive care unitNeonatal-perinatal medicine fellowsCentral line placementPost-intervention analysisCohort studyCentral cathetersCare unitCatheter maintenanceLine daysNeedle stickInsertion successComplicationsLine placementSignificant reductionPhlebitis
2018
Validation of the International Guide for Monitoring Child Development demonstrates good sensitivity and specificity in four diverse countries
Ertem IO, Krishnamurthy V, Mulaudzi MC, Sguassero Y, Bilik B, Srinivasan R, Balta H, Gulumser O, Gan G, Calvocoressi L, Johnson B, Shabanova V, Forsyth B. Validation of the International Guide for Monitoring Child Development demonstrates good sensitivity and specificity in four diverse countries. Acta Paediatrica 2018, 108: 1074-1086. PMID: 30472813, PMCID: PMC6520130, DOI: 10.1111/apa.14661.Peer-Reviewed Original ResearchReducing Radiation Exposure in Cardiac Catheterizations for Congenital Heart Disease
Patel C, Grossman M, Shabanova V, Asnes J. Reducing Radiation Exposure in Cardiac Catheterizations for Congenital Heart Disease. Pediatric Cardiology 2018, 40: 638-649. PMID: 30542920, DOI: 10.1007/s00246-018-2039-9.Peer-Reviewed Original ResearchConceptsCatheterization labRadiation exposureCardiac catheterizationYale-New Haven Children's HospitalDAP/Patent ductus arteriosusAtrial septal defectCongenital heart diseaseDose area productSystems-based interventionsCardiac catheterization labCongenital cardiac catheterizationTotal air kermaPost-intervention dataRadiation dose reductionAir kermaQuality improvement strategiesDuctus arteriosusTranscatheter pulmonaryChildren's HospitalDA dosesSeptal defectHeart diseaseLow fluoroscopyProcedure typeUS National Trends in Pediatric Deaths From Prescription and Illicit Opioids, 1999-2016
Gaither JR, Shabanova V, Leventhal JM. US National Trends in Pediatric Deaths From Prescription and Illicit Opioids, 1999-2016. JAMA Network Open 2018, 1: e186558. PMID: 30646334, PMCID: PMC6324338, DOI: 10.1001/jamanetworkopen.2018.6558.Peer-Reviewed Original ResearchConceptsOpioid poisoningPediatric deathsMortality rateUS national trendsPublic health problemPediatric mortality rateNational trendsPublic health officialsIllicit opioidsPrescription opioidsAge-specific mortality ratesOpioid deathsOpioid epidemicMAIN OUTCOMEOpioidsHealth problemsOpioid crisisPoisson regressionSynthetic opioidsDisease controlMortality dataHealth officialsDeathMedical facilitiesChildrenFactors Associated with Adverse Outcomes among Febrile Young Infants with Invasive Bacterial Infections
Pruitt CM, Neuman MI, Shah SS, Shabanova V, Woll C, Wang ME, Alpern ER, Williams DJ, Sartori L, Desai S, Leazer RC, Marble RD, McCulloh RJ, DePorre AG, Rooholamini SN, Lumb CE, Balamuth F, Shin S, Aronson PL, Collaborative F, Nigrovic L, Browning W, Mitchell C, Peaper D, Feldman E. Factors Associated with Adverse Outcomes among Febrile Young Infants with Invasive Bacterial Infections. The Journal Of Pediatrics 2018, 204: 177-182.e1. PMID: 30297292, PMCID: PMC6309646, DOI: 10.1016/j.jpeds.2018.08.066.Peer-Reviewed Original ResearchConceptsInvasive bacterial infectionsFebrile young infantsAdverse outcomesBacterial meningitisYoung infantsIll appearanceFebrile infantsBacterial infectionsRetrospective cohort studyMedical record reviewLocal microbiology laboratoryMixed-effects logistic regressionElectronic medical record systemDays of ageIll appearingNeurologic sequelaeCohort studyMedical record systemClinical factorsMedication receiptMechanical ventilationRecord reviewClinical dataInclusion criteriaMeningitisSimilarities and differences in child development from birth to age 3 years by sex and across four countries: a cross-sectional, observational study
Ertem IO, Krishnamurthy V, Mulaudzi MC, Sguassero Y, Balta H, Gulumser O, Bilik B, Srinivasan R, Johnson B, Gan G, Calvocoressi L, Shabanova V, Forsyth BWC. Similarities and differences in child development from birth to age 3 years by sex and across four countries: a cross-sectional, observational study. The Lancet Global Health 2018, 6: e279-e291. PMID: 29433666, DOI: 10.1016/s2214-109x(18)30003-2.Peer-Reviewed Original ResearchConceptsMedian ageHealthy childrenObservational studyChild healthMotor milestonesHealthy subsampleHealth statusEunice Kennedy Shriver National InstituteDevelopmental milestonesChild health statusGross motor milestonesMonitoring Child DevelopmentFine motor milestonesAge 3 yearsSelf-help domainLanguage milestonesPerinatal complicationsMiddle-income countriesLow birthweightChronic illnessHealth clinicsAge of attainmentFine motorChild developmentPercentile age
2017
Risk factors for tracheostomy requirement in extremely low birth weight infants
Levit OL, Shabanova V, Bazzy-Asaad A, Bizzarro MJ, Bhandari V. Risk factors for tracheostomy requirement in extremely low birth weight infants. The Journal Of Maternal-Fetal & Neonatal Medicine 2017, 31: 447-452. PMID: 28139937, DOI: 10.1080/14767058.2017.1287895.Peer-Reviewed Original ResearchMeSH KeywordsAirway ExtubationCase-Control StudiesFemaleGestational AgeHumansInfantInfant, Extremely Low Birth WeightInfant, Extremely PrematureInfant, NewbornIntubation, IntratrachealMalePregnancyRespiration, ArtificialRetrospective StudiesRisk FactorsSeverity of Illness IndexTime FactorsTracheostomyConceptsLow birth weight infantsOdds of tracheostomyBirth weight infantsELBW infantsWeight infantsEndotracheal tubeRisk of tracheostomyPresence of comorbiditiesUse of steroidsCase-control studyConditional logistic regressionNumber of intubationsGreater cumulative exposureIntubation episodesTracheostomy requirementExtubation attemptGestational ageEpisodes/Risk factorsTracheostomyPrevious episodesCumulative exposurePoisson regressionCumulative daysInfants
2016
Prediction of Catheter-Associated Thrombosis in Critically Ill Children
Marquez A, Shabanova V, Faustino EV. Prediction of Catheter-Associated Thrombosis in Critically Ill Children. Pediatric Critical Care Medicine 2016, 17: e521-e528. PMID: 27662566, DOI: 10.1097/pcc.0000000000000958.Peer-Reviewed Original ResearchConceptsCatheter-associated thrombosisCentral venous cathetersVenous cathetersIll childrenRecent surgeryHigh riskCatheter-associated deep venous thrombosisMulticenter prospective cohort studyBlood product transfusionDeep venous thrombosisProspective cohort studyCritically Ill ChildrenSeverity of illnessRisk prediction modelProduct transfusionCohort studyVenous thrombosisGroup of childrenSubclavian veinActive surveillanceThrombosisCatheterSecondary analysisLogistic regressionCharacteristic curve
2014
A randomized controlled trial of capnography during sedation in a pediatric emergency setting
Langhan ML, Shabanova V, Li FY, Bernstein SL, Shapiro ED. A randomized controlled trial of capnography during sedation in a pediatric emergency setting. The American Journal Of Emergency Medicine 2014, 33: 25-30. PMID: 25445871, PMCID: PMC4272647, DOI: 10.1016/j.ajem.2014.09.050.Peer-Reviewed Original ResearchConceptsEpisodes of hypoventilationOxygen desaturationIntervention groupStandard monitoringPediatric emergency department patientsEmergency department patientsSedation of childrenPediatric emergency departmentPediatric emergency settingRates of interventionFrequency of interventionsRespiratory depressionPrimary outcomeDepartment patientsEmergency departmentProcedural sedationEmergency settingHigher oddsHypoventilationCapnography monitorControl groupSedationStandard modalityTimely interventionCapnographyEffect of vitamin D–binding protein genotype on the development of asthma in children
Navas-Nazario A, Li FY, Shabanova V, Weiss P, Cole DE, Carpenter TO, Bazzy-Asaad A. Effect of vitamin D–binding protein genotype on the development of asthma in children. Annals Of Allergy Asthma & Immunology 2014, 112: 519-524. PMID: 24745702, PMCID: PMC4070170, DOI: 10.1016/j.anai.2014.03.017.Peer-Reviewed Original ResearchMeSH KeywordsAsthmaChild, PreschoolCholestanetriol 26-MonooxygenaseConnecticutCytochrome P450 Family 2FemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHispanic or LatinoHumansInfantMalePolymorphism, Single NucleotideReceptors, CalcitriolRetrospective StudiesVitamin DVitamin D-Binding ProteinConceptsDevelopment of asthmaVitamin DGC genotypeVitamin D metabolite levelsRetrospective medical record reviewVitamin D insufficiencyMedical record reviewCurrent clinical dataSingle nucleotide polymorphismsVitamin D metabolitesGC single nucleotide polymorphismsHispanic populationPotential vitamin DMonths of ageD insufficiencyAsthma morbidityHealthy infantsRecord reviewD metabolitesHealthy childrenInflammatory diseasesNucleotide polymorphismsClinical dataProtective effectAsthma
2013
The impact of limited English proficiency on asthma action plan use
Riera A, Navas-Nazario A, Shabanova V, Vaca FE. The impact of limited English proficiency on asthma action plan use. Journal Of Asthma 2013, 51: 178-184. PMID: 24147607, DOI: 10.3109/02770903.2013.858266.Peer-Reviewed Original ResearchConceptsAsthma action plan useAction plan usePediatric emergency departmentPlan useLEP caregiversExact testCaregivers' reasonsQualified health centersFisher's exact testPhysician attentivenessSymptom managementChief complaintEmergency departmentChild's asthmaLimited English proficiencyHealth centersAge of childrenWhite raceMild/Caregiver educationAsthmaLatino ethnicityCaregivers' abilityPrivate insuranceCaregivers