2021
Age-Dependent Heterogeneity in the Efficacy of Prophylaxis With Enoxaparin Against Catheter-Associated Thrombosis in Critically Ill Children: A Post Hoc Analysis of a Bayesian Phase 2b Randomized Clinical Trial.
Faustino EVS, Raffini LJ, Hanson SJ, Cholette JM, Pinto MG, Li S, Kandil SB, Nellis ME, Shabanova V, Silva CT, Tala JA, McPartland T, Spinella PC. Age-Dependent Heterogeneity in the Efficacy of Prophylaxis With Enoxaparin Against Catheter-Associated Thrombosis in Critically Ill Children: A Post Hoc Analysis of a Bayesian Phase 2b Randomized Clinical Trial. Critical Care Medicine 2021, 49: e369-e380. PMID: 33566465, PMCID: PMC7979442, DOI: 10.1097/ccm.0000000000004848.Peer-Reviewed Original ResearchMeSH KeywordsAnticoagulantsCatheterization, Central VenousChildChild, PreschoolCritical IllnessEnoxaparinFemaleHumansInfantMaleOutcome Assessment, Health CarePre-Exposure ProphylaxisThrombosisVenous ThrombosisConceptsCentral venous catheter-associated deep venous thrombosisCatheter-associated deep venous thrombosisCentral venous cathetersEfficacy of prophylaxisDeep venous thrombosisAge-dependent heterogeneityAnti-Xa levelsVenous cathetersVenous thrombosisFactor VIII activityThrombin generationPlatelet countClinical trialsIll childrenPhase 2bVIII activityLow factor VIII activityCatheter-Associated ThrombosisInternational units/mLMinimum platelet countOlder childrenCritically Ill ChildrenEndogenous thrombin potentialHigher platelet countsPost Hoc Analysis
2020
Factors in Early Feeding Practices That May Influence Growth and the Challenges That Arise in Growth Outcomes Research
Fabrizio V, Shabanova V, Taylor SN. Factors in Early Feeding Practices That May Influence Growth and the Challenges That Arise in Growth Outcomes Research. Nutrients 2020, 12: 1939. PMID: 32629763, PMCID: PMC7399918, DOI: 10.3390/nu12071939.Peer-Reviewed Original ResearchConceptsWeeks gestational ageGestational agePreterm infantsEarly feeding practicesInfant growth trajectoriesFetal growth chartsSingle-center investigationInitial hospitalizationParenteral nutritionImproved outcomesInclusion criteriaFeeding practicesGrowth chartsNutritional practicesFirst weekHospital growthNutritional factorsInfantsQuartileCenter investigationLess daysOutcomes researchCaloric densityHospitalizationCohort effects