Effect of testosterone replacement on measures of mobility in older men with mobility limitation and low testosterone concentrations: secondary analyses of the Testosterone Trials
Bhasin S, Ellenberg SS, Storer TW, Basaria S, Pahor M, Stephens-Shields AJ, Cauley JA, Ensrud KE, Farrar JT, Cella D, Matsumoto AM, Cunningham GR, Swerdloff RS, Wang C, Lewis CE, Molitch ME, Barrett-Connor E, Crandall JP, Hou X, Preston P, Cifelli D, Snyder PJ, Gill TM. Effect of testosterone replacement on measures of mobility in older men with mobility limitation and low testosterone concentrations: secondary analyses of the Testosterone Trials. The Lancet Diabetes & Endocrinology 2018, 6: 879-890. PMID: 30366567, PMCID: PMC6816466, DOI: 10.1016/s2213-8587(18)30171-2.Peer-Reviewed Original ResearchConceptsEffects of testosteroneSelf-reported mobility limitationsPlacebo-treated menTestosterone-treated menLow testosterone concentrationsPlacebo groupMobility limitationsTestosterone concentrationsTestosterone groupTestosterone TrialsOlder menHemoglobin concentrationMin walk test distanceSelf-reported physical functionPlacebo gel dailyPatient Global ImpressionBaseline gait speedShort Form-36Total testosterone concentrationsPost-intervention assessmentModified intentionTreat populationTestosterone therapyTestosterone gelForm-36