2021
Biocompatibility of platinum-based bulk metallic glass in orthopedic applications
Loye AM, Kwon HK, Dellal D, Ojeda R, Lee S, Davis R, Nagle N, Doukas PG, Schroers J, Lee FY, Kyriakides TR. Biocompatibility of platinum-based bulk metallic glass in orthopedic applications. Biomedical Materials 2021, 16: 045018. PMID: 33873168, DOI: 10.1088/1748-605x/abf981.Peer-Reviewed Original ResearchConceptsBulk metallic glassPt-BMGPlatinum-based bulk metallic glassMetallic glassesConventional metallic implantsCorrosion resistanceHigh strengthMechanical testingOrthopedic applicationsBone applicationsMetallic implantsMicro-computed tomographyAmorphous metalsTitaniumWearBiocompatibilitySimilar biocompatibilityFurther processingGlassDuctilityNanopatternsNanoscaleApplicationsMesenchymal stem cellsStrengthBiocompatibility of nanomaterials and their immunological properties
Kyriakides TR, Raj A, Tseng TH, Xiao H, Nguyen R, Mohammed FS, Halder S, Xu M, Wu MJ, Bao S, Sheu WC. Biocompatibility of nanomaterials and their immunological properties. Biomedical Materials 2021, 16: 042005. PMID: 33578402, PMCID: PMC8357854, DOI: 10.1088/1748-605x/abe5fa.Peer-Reviewed Original ResearchConceptsMetal/metal oxideBiocompatibility of nanomaterialsNanomaterialsNovel sensingMetal oxidesBiocompatibilityOverall biocompatibilityBulk materialClinical trialsOccupational exposureTherapeutic approachesSystemic effectsNanotoxicityClinical useFabricationPutative negative effectsImmunological propertiesSensingCell typesOxideLiposomesHost proteinsReciprocal interactionsApplicationsCarbon
2009
Bulk metallic glasses for biomedical applications
Schroers J, Kumar G, Hodges T, Chan S, Kyriakides T. Bulk metallic glasses for biomedical applications. JOM 2009, 61: 21-29. DOI: 10.1007/s11837-009-0128-1.Peer-Reviewed Original ResearchBulk metallic glassMetallic glassesBiomedical applicationsField of biomaterialsMetallic biomaterialsImplant applicationsExcellent combinationMaterial propertiesSuperior propertiesComplex implantsSurface topographyDesirable biological responsesForeign body responseBiomaterialsProcessing capabilitiesFlexible chemistryGlassPropertiesAtomic structureApplicationsBiocompatibilityBody responseDevicesMaterials