2017
Thyroid hormone- and estrogen receptor interactions with natural ligands and endocrine disruptors in the cerebellum
Zsarnovszky A, Kiss D, Jocsak G, Nemeth G, Toth I, Horvath TL. Thyroid hormone- and estrogen receptor interactions with natural ligands and endocrine disruptors in the cerebellum. Frontiers In Neuroendocrinology 2017, 48: 23-36. PMID: 28987779, DOI: 10.1016/j.yfrne.2017.10.001.Peer-Reviewed Original ResearchConceptsEffects of phytoestrogensThyroid hormonesBrain functionNormal physiological settingsMetabolic parametersMature brainEstrogen receptor interactionSteroid hormonesBrain developmentHormoneHomeostatic parametersIntercellular actionsHormonal mechanismsReceptor interactionNatural ligandEnergy metabolismCerebellumEndocrine disruptorsPhytoestrogensPivotal rolePhysiological settingsMetabolismGliaEstrogenNeurons
2001
Brain androgen and progesterone metabolizing enzymes: biosynthesis, distribution and function
Lephart E, Lund T, Horvath T. Brain androgen and progesterone metabolizing enzymes: biosynthesis, distribution and function. Brain Research Reviews 2001, 37: 25-37. PMID: 11744072, DOI: 10.1016/s0165-0173(01)00111-4.Peer-Reviewed Original ResearchConceptsDimorphic brain structuresAnteroventral periventricular nucleusBrain structuresEffects of phytoestrogensLow phytoestrogen dietPeripheral tissue sitesBrain aromatase cytochrome P450Brain androgenPhytoestrogen dietFemale ratsPeriventricular nucleusPreoptic areaCalcium-binding proteinsAromatase cytochrome P450Dimorphic nucleusTissue sitesCalbindinSteroid productsPotential roleSpatial memoryVisual-spatial memoryP450aroCytochrome P450Recent reportsPhytoestrogens