2019
Molecular constituents and localization of the ionotropic GABA receptor complex in vivo
Tomita S. Molecular constituents and localization of the ionotropic GABA receptor complex in vivo. Current Opinion In Neurobiology 2019, 57: 81-86. PMID: 30784980, PMCID: PMC6629498, DOI: 10.1016/j.conb.2019.01.017.Peer-Reviewed Original ResearchConceptsNative receptor complexReceptor complexPore-forming subunitMolecular constituentsNew mechanistic insightsProtein familySubunit assemblyMajor molecular constituentsProperties of GABASynaptic localizationIonotropic GABA receptorsPrimary neuronsMechanistic insightsGABA receptor complexNative GABAReceptor regulationGABA receptorsNeuroligin-2R complexesGABAFast inhibitionPharmacological propertiesComplexesLocalizationSubunits
2017
Assembly rules for GABAA receptor complexes in the brain
Martenson JS, Yamasaki T, Chaudhury NH, Albrecht D, Tomita S. Assembly rules for GABAA receptor complexes in the brain. ELife 2017, 6: e30826. PMID: 28816653, PMCID: PMC5577914, DOI: 10.7554/elife.27443.Peer-Reviewed Original ResearchGARLH Family Proteins Stabilize GABAA Receptors at Synapses
Yamasaki T, Hoyos-Ramirez E, Martenson JS, Morimoto-Tomita M, Tomita S. GARLH Family Proteins Stabilize GABAA Receptors at Synapses. Neuron 2017, 93: 1138-1152.e6. PMID: 28279354, PMCID: PMC5347473, DOI: 10.1016/j.neuron.2017.02.023.Peer-Reviewed Original ResearchConceptsInhibitory transmissionSynaptic transmissionSynaptic localizationInhibitory synaptic transmissionFast inhibitory transmissionFast synaptic transmissionIonotropic neurotransmitter receptorsLigand-gated ion channelsAuxiliary subunitsGABAA receptorsIonotropic GABANeurotransmitter receptorsNeuroligin-2GABAReceptorsAnion channelIon channelsBrainHippocampusFindingsSynapses