2024
Assessment of the productivity loss due to leading maternal ill-health conditions: a follow-up study of a prospective pregnancy cohort in rural Sri Lanka
Gunarathna S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Assessment of the productivity loss due to leading maternal ill-health conditions: a follow-up study of a prospective pregnancy cohort in rural Sri Lanka. BMJ Open 2024, 14: e082798. PMID: 39477261, PMCID: PMC11529687, DOI: 10.1136/bmjopen-2023-082798.Peer-Reviewed Original ResearchConceptsIll-health conditionsRural Sri LankaPregnant womenPregnancy cohortFollow-up study of womenFollow-up studyProspective pregnancy cohortRajarata Pregnancy CohortSecondary outcome measuresMonthly household expenditureVaginal bleedingProductivity lossStudy of womenPrimary outcome measurePregnancy follow-upMedical careOutcome measuresHigher absenteeismNausea and vomitingPresenteeismHighest prevalenceAbsenteeismThird trimesterWomenRecommended priorities
2023
Out-of-Pocket Expenditure for Antenatal Care Amid Free Health Care Provision: Evidence From a Large Pregnancy Cohort in Rural Sri Lanka
Gunarathna S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Out-of-Pocket Expenditure for Antenatal Care Amid Free Health Care Provision: Evidence From a Large Pregnancy Cohort in Rural Sri Lanka. Global Health Science And Practice 2023, 11: e2200410. PMID: 37903576, PMCID: PMC10615247, DOI: 10.9745/ghsp-d-22-00410.Peer-Reviewed Original ResearchConceptsMean OOP expenditureAntenatal careLarge pregnancy cohortPrivate health facilitiesPregnant womenHealth facilitiesOOP expenditureMaternal morbidityIndependent predictorsPrevious pregnancyPregnancy cohortHealth service utilizationInterviewer-administered questionnaireSignificant independent predictorsGovernment health facilitiesGovernment health servicesCare modeLaboratory investigationsHealth care usersSelf-administered questionnaireSri Lankan settingMonthly household incomeHealth care provisionANC visitsThird trimesterIncorporating early pregnancy mental health screening and management into routine maternal care: experience from the Rajarata Pregnancy Cohort (RaPCo), Sri Lanka
Agampodi T, Amarasinghe G, Wickramasinghe A, Wickramasinghe N, Warnasekara J, Jayasinghe I, Hettiarachchi A, Nimesha D, Dilshani T, Senadheera S, Agampodi S. Incorporating early pregnancy mental health screening and management into routine maternal care: experience from the Rajarata Pregnancy Cohort (RaPCo), Sri Lanka. BMJ Global Health 2023, 8: e012852. PMID: 37748792, PMCID: PMC10533714, DOI: 10.1136/bmjgh-2023-012852.Peer-Reviewed Original ResearchConceptsEdinburgh Postnatal Depression ScaleMental health screeningMental health problemsPregnancy cohortSecond trimesterEarly pregnancyHealth screeningClinical InterviewHealth problemsPregnancy care programsRoutine maternal careTertiary care hospitalMental health service provisionPrimary healthcare levelHigher EPDS scoresPostnatal Depression ScaleWeeks of periodPregnancy-associated conditionsMental health gapPatient-centered careHealth service provisionHealth surveillance systemsCare hospitalMiddle-income countriesPregnant womenCohort Profile: The Rajarata Pregnancy Cohort (RaPCo)
Agampodi S, Wickramasinghe N, Agampodi T. Cohort Profile: The Rajarata Pregnancy Cohort (RaPCo). Anuradhapura Medical Journal 2023, 17: 31. DOI: 10.4038/amj.v17i1.7757.Peer-Reviewed Original ResearchMaternal morbidityFirst trimesterPregnancy cohortPregnant womenFirst antenatal clinic visitEarly pregnancy miscarriageFatty liver gradePregnancy care programsFatty liver indexGestational age neonatesAntenatal clinic visitPregnancy outcome dataAnemic pregnant womenSignificant risk factorsComprehensive mental healthBaseline data collectionGestational diabetesAge neonatesClinic visitsCohort womenMetabolic syndromeMetabolic derangementsEarly pregnancyEntire cohortLiver indexEarly pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka
Jayasinghe I, Agampodi T, Dissanayake A, Agampodi S. Early pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka. BMC Pregnancy And Childbirth 2023, 23: 231. PMID: 37020187, PMCID: PMC10074348, DOI: 10.1186/s12884-023-05548-y.Peer-Reviewed Original ResearchConceptsGestational agePreterm birthPregnancy outcomesPregnant womenMetabolic syndromePregnancy cohortJoint Interim Statement criteriaFirst trimester pregnant womenMajor pregnancy outcomesSouth Asian pregnant womenAdverse pregnancy outcomesNeonatal birth weightGestational weight gainMedian gestational ageProspective cohort studyLive singleton birthsSignificant risk predictorAsian pregnant womenConclusionPregnant womenFPG thresholdMetS prevalenceCohort studyCumulative incidenceProspective cohortMetS definitionsSerum creatinine and estimated glomerular filtration rate (eGFR) in early pregnancy and changes during the pregnancy
Agampodi S, Agampodi T, Amarasinghe G, Warnasekara J, Hettiarachchi A, Jayasinghe I, Koralegedara I, Abeyrathna P, Srimantha S, de Silva F, Gunarathne S, Wickramasinghe N. Serum creatinine and estimated glomerular filtration rate (eGFR) in early pregnancy and changes during the pregnancy. PLOS Global Public Health 2023, 3: e0000443. PMID: 36962935, PMCID: PMC10021427, DOI: 10.1371/journal.pgph.0000443.Peer-Reviewed Original ResearchGlomerular filtration rateWeeks of gestationRenal functionPregnant womenNonpregnant womenSerum creatinineSecond trimesterEarly pregnancyFiltration rateClinical practiceCommunity-based prospective cohort studyProspective population-based studyPre-existing medical conditionsProspective cohort studyHealthy pregnant womenCommunity-based cohortPopulation-based studyDifferent age strataMean eGFRCohort studyNewborn outcomesNonpregnant groupPregnancy cohortFirst trimesterMean SCr
2022
The geo-spatial perspective of biological, social and environmental determinants of early pregnancy anaemia in rural Sri Lanka: Need for context-specific approaches on prevention
Amarasinghe G, Agampodi T, Mendis V, Agampodi S. The geo-spatial perspective of biological, social and environmental determinants of early pregnancy anaemia in rural Sri Lanka: Need for context-specific approaches on prevention. Geospatial Health 2022, 17 PMID: 36468596, DOI: 10.4081/gh.2022.1110.Peer-Reviewed Original ResearchConceptsPrevalence of anemiaEarly pregnancyPregnant womenRisk factorsFirst trimester pregnant womenHigher anemia prevalenceAntenatal care programsEnvironmental risk factorsHeterogeneous risk factorsMaternal anemiaPregnancy anemiaPregnancy cohortAnemia prevalenceDietary patternsHigh prevalenceAnemiaCare programRural Sri LankaPrevalenceSocioeconomic disparitiesPregnancyHealth DivisionEthnic distributionSignificant differencesAnuradhapura districtFatty Liver Index is a valid predictor of non-alcoholic fatty liver disease (NAFLD) in pregnancy
Koralegedara IS, Warnasekara JN, Rathnayake A, Dayaratne KG, Agampodi SB. Fatty Liver Index is a valid predictor of non-alcoholic fatty liver disease (NAFLD) in pregnancy. BMJ Open Gastroenterology 2022, 9: e000913. PMID: 35728866, PMCID: PMC9214354, DOI: 10.1136/bmjgast-2022-000913.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseFatty liver indexAdverse pregnancy outcomesFatty liver diseasePregnant womenPregnancy outcomesLiver diseaseFatty liverLiver indexFirst trimester pregnant womenGamma-glutamyl transferase levelsBody mass indexPeriod of gestationLogistic regression modelsBinary logistic regression modelIndependent predictorsMass indexPregnancy cohortEarly pregnancyMean ageTransferase levelsLiver enzymesUltrasound scanGeneral populationHealth setupDoes Being Diagnosed As Anemic in Early Pregnancy Have an Impact on the Household Expenditure for Food? Evidence From a Maternal Cohort in Rural Sri Lanka
Gunarathne S, Amarasinghe G, Agampodi T, Wickramasinghe N, Mendis V, Prasanna I, Agampodi S. Does Being Diagnosed As Anemic in Early Pregnancy Have an Impact on the Household Expenditure for Food? Evidence From a Maternal Cohort in Rural Sri Lanka. Current Developments In Nutrition 2022, 6: 654. PMCID: PMC9193294, DOI: 10.1093/cdn/nzac061.038.Peer-Reviewed Original ResearchNon-anaemic womenEarly pregnancyPregnant womenRural Sri LankaFirst trimester pregnant womenPublic health midwivesHousehold food expenditureThird of pregnanciesAnemic pregnant womenMann-Whitney U testDiagnosis of anemiaMonthly household incomeLifestyle modificationHemoglobin levelsPregnancy cohortThird trimesterMean ageModerate anemiaMaternal cohortAppropriate treatmentHousehold economic statusNutritional educationSelf-administrated questionnairePregnancyAnemiaFeasibility of using telephone interviews and internet-based message services during the COVID-19 pandemic in rural Sri Lanka: experiences of the Rajarata Pregnancy Cohort
Jayasinghe I, Wickramasinghe Y, Kurera DM, Samarakoon N, Rupasinghe I, Ponmalay P, Agampodi SB. Feasibility of using telephone interviews and internet-based message services during the COVID-19 pandemic in rural Sri Lanka: experiences of the Rajarata Pregnancy Cohort. Rural And Remote Health 2022, 22: 7442. PMID: 35546146, DOI: 10.22605/rrh7442.Peer-Reviewed Original ResearchConceptsTelephone interviewsPregnancy cohortCOVID-19 pandemicTelephone-based strategyHealth message deliveryHealth promotion initiativesLow-resource settingsPregnant womenPopulation health researchersRural Sri LankaPromotion initiativesHealth disparitiesRural areasCohortSelection biasHealth researchersMiddle-income nationsPandemicDeliveryParticipantsLocal settingProper assessmentImplementation of researchSettingSri Lanka
2021
The hidden burden of adolescent pregnancies in rural Sri Lanka; findings of the Rajarata Pregnancy Cohort
Agampodi TC, Wickramasinghe ND, Jayakodi HG, Amarasinghe GS, Warnasekara JN, Hettiarachchi AU, Jayasinghe IU, Koralegedara IS, Gunarathne SP, Somasiri DK, Agampodi SB. The hidden burden of adolescent pregnancies in rural Sri Lanka; findings of the Rajarata Pregnancy Cohort. BMC Pregnancy And Childbirth 2021, 21: 494. PMID: 34233652, PMCID: PMC8265066, DOI: 10.1186/s12884-021-03977-1.Peer-Reviewed Original ResearchConceptsEdinburgh Postpartum Depression ScaleAdolescent pregnancyPregnancy cohortPregnant womenRural Sri LankaLower body mass indexUtilization of SexualLower hemoglobin levelsBody mass indexPostpartum Depression ScaleReproductive health servicesMental health statusPeriod of gestationHealth care servicesLow education levelMental health effectsResultsBaseline dataBlood investigationsPrimigravida mothersHemoglobin levelsMass indexFirst pregnancyClinical examinationMaternal healthSRH servicesCan Homocysteine Be Used to Identify Vitamin B12 or Folate Deficiencies During Pregnancy in Low Resource Settings?
Amarasinghe G, Jayasinghe I, Hettiarachchi A, Koralegedara I, Kappagoda C, Mendis W, Agampodi T, Agampodi S. Can Homocysteine Be Used to Identify Vitamin B12 or Folate Deficiencies During Pregnancy in Low Resource Settings? Current Developments In Nutrition 2021, 5: 5140707. PMCID: PMC8181706, DOI: 10.1093/cdn/nzab046_004.Peer-Reviewed Original ResearchAnemic pregnant womenPregnant womenHomocysteine levelsFolate deficiencyB12 levelsB12 deficiencyVitamin B12Folate levelsVitamin B12/folate deficiencyMedian hemoglobin levelSerum homocysteine levelsSerum total homocysteineWeeks of gestationRole of homocysteineUniversal iron supplementationElevated homocysteine levelsLow-resource settingsMiddle-income settingsHemoglobin levelsPregnancy cohortSecond trimesterHospital clinicIron supplementationTotal homocysteineNegative testHousehold Food Expenditure Share During Pregnancy: Evidence From Rural Sri Lanka
Gunarathne S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Household Food Expenditure Share During Pregnancy: Evidence From Rural Sri Lanka. Current Developments In Nutrition 2021, 5: 753. PMCID: PMC8181375, DOI: 10.1093/cdn/nzab046_050.Peer-Reviewed Original ResearchPregnant womenHousehold food expenditureMean monthly household incomeRural pregnant womenIncome quintileSelf-administered questionnaireMonthly household incomeHousehold incomeProspective cohortPregnancy cohortMean ageHighest quintilePositive correlationTrimesterPregnancyRural Sri LankaSignificant positive correlationWeak positive correlationQuintileMeasures ANOVAOne-way ANOVASignificant differencesCohortNutritional Status and Additional Expenditure on Food During Pregnancy: Evidence From the Rajarata Pregnancy Cohort
Gunarathne S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Nutritional Status and Additional Expenditure on Food During Pregnancy: Evidence From the Rajarata Pregnancy Cohort. Current Developments In Nutrition 2021, 5: 5140754. PMCID: PMC8181471, DOI: 10.1093/cdn/nzab046_051.Peer-Reviewed Original ResearchPoor nutritional statusNutritional statusPregnancy cohortSignificant differencesMean monthly household incomeSelf-administered questionnaireMonthly household incomeDifferent nutritional statusUnderweight mothersProspective cohortUnderweight groupMean agePregnant womenPregnant mothersUnderweight categoryObjective adherenceTrimesterAnthropometric measurementsFood consumption patternsHousehold economic statusRural Sri LankaCohortIncome quintileMothersPregnancyA self‐applied valid scale for rapid tracking of household food insecurity among pregnant women in Sri Lanka
Agampodi TC, Hromi‐Fiedler A, Agampodi SB, Amarasinghe GS, Wickramasinghe ND, Jayasinghe IU, Hettiarachchi AU, Perez‐Escamilla R. A self‐applied valid scale for rapid tracking of household food insecurity among pregnant women in Sri Lanka. Maternal And Child Nutrition 2021, 17: e13165. PMID: 33733618, PMCID: PMC8189217, DOI: 10.1111/mcn.13165.Peer-Reviewed Original ResearchConceptsPsychological distressConcurrent validityModel-fitting analysesItem severity scoresGood model fitCognitive testingAdult versionParameter logistic modelPregnant womenPsychometric propertiesSecurity ScaleValid scaleCaribbean Food Security ScalePsychometric validationCOVID-19 pandemicModel fitDistressSTATA version 14Item 8Valid toolPregnancy cohortSeverity scoreSpecial clinicFood Security ScaleHousehold food insecurity
2020
The Rajarata Pregnancy Cohort (RaPCo): study protocol
Agampodi TC, Wickramasinghe ND, Prasanna RIR, Irangani MKL, Banda JMS, Jayathilake PMB, Hettiarachchi A, Amarasinghe G, Jayasinghe I, Koralagedara I, Gunarathne SP, Wickramage S, Warnasekara J, Lokunarangoda N, Mendis V, Dissanayaka AK, Premadasa J, Hettigama N, Koralagedara D, Weerasinghe M, Malawanage K, Jayakodi H, Wickramasinghe A, Agampodi SB. The Rajarata Pregnancy Cohort (RaPCo): study protocol. BMC Pregnancy And Childbirth 2020, 20: 374. PMID: 32586287, PMCID: PMC7318435, DOI: 10.1186/s12884-020-03056-x.Peer-Reviewed Original ResearchConceptsMaternal mental healthMaternal deathsMental healthSocial determinantsPregnancy cohortObstetric transitionEligible pregnant womenProspective cohort studyMaternal health outcomesMaternal mortality ratePreventable maternal deathsMaternal care programmeChild outcome dataAntenatal depressionCohort studyMiddle-income countriesFirst trimesterNeonatal periodPregnant womenClinical examinationMaternal healthEarly postpartumMaternal cohortStudy protocolMethodsThe study