2001
Semaphorin-mediated axonal guidance via Rho-related G proteins
Liu B, Strittmatter S. Semaphorin-mediated axonal guidance via Rho-related G proteins. Current Opinion In Cell Biology 2001, 13: 619-626. PMID: 11544032, DOI: 10.1016/s0955-0674(00)00260-x.Peer-Reviewed Original ResearchNogo: A Molecular Determinant of Axonal Growth and Regeneration
Grandpré T, Strittmatter S. Nogo: A Molecular Determinant of Axonal Growth and Regeneration. The Neuroscientist 2001, 7: 377-386. PMID: 11597097, DOI: 10.1177/107385840100700507.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxonsBrainBrain InjuriesGrowth InhibitorsHumansMammalsModels, NeurologicalMyelin ProteinsNerve RegenerationNeuronal PlasticityNogo ProteinsConceptsCentral nervous systemCNS environmentNervous systemAdult mammalian central nervous systemEnhanced axonal regenerationPersistent functional deficitsMammalian central nervous systemPeripheral nervous systemNeurite outgrowth inhibitorIntegral membrane proteinsCNS traumaFunctional recoveryReactive astrocytesVivo neutralizationCNS injuryAxonal regenerationFunctional deficitsGlial scarNonpermissive natureOutgrowth inhibitorCNS axonsAxonal growthAxonal elongationMembrane proteinsAxon elongation
1992
GAP-43 as a modulator of G protein transduction in the growth cone.
Strittmatter SM. GAP-43 as a modulator of G protein transduction in the growth cone. Perspectives On Developmental Neurobiology 1992, 1: 13-9. PMID: 1364285.Peer-Reviewed Original ResearchConceptsGrowth cone membraneGrowth cone motilityMolecular mechanismsSame cellular functionCone motilityG protein-coupled transmembrane receptorsAmino acid stretchComplex cellular propertiesCone membraneGrowth conesNeurotransmitter releaseGrowth cone functionPossible molecular mechanismsCellular functionsGAP-43 functionHydrophilic proteinProtein transductionGAP-43Transmembrane receptorsGAP-43 regulationCysteine residuesTransduction systemSynaptic plasticityAmino terminusCell shape