2020
The Neurobiology of Impulsive Decision-Making and Reinforcement Learning in Nonhuman Animals
Groman SM. The Neurobiology of Impulsive Decision-Making and Reinforcement Learning in Nonhuman Animals. Current Topics In Behavioral Neurosciences 2020, 47: 23-52. PMID: 32157666, DOI: 10.1007/7854_2020_127.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsChoice BehaviorDecision MakingDopamineHumansImpulsive BehaviorNeurobiologyReinforcement, PsychologyRewardConceptsImpulsive choiceNonhuman animalsReinforcement learning processSophisticated behavioralImpulsive decisionNeural mechanismsNeuroscience techniquesNeurobiological mechanismsNeuromodulatory systemsBehavioral heterogeneityApplication of reinforcementLearning processNeurochemical basisMental illnessIntegration of reinforcementImpulsivityPathological levels
2014
Dissecting impulsivity and its relationships to drug addictions
Jentsch JD, Ashenhurst JR, Cervantes MC, Groman SM, James AS, Pennington ZT. Dissecting impulsivity and its relationships to drug addictions. Annals Of The New York Academy Of Sciences 2014, 1327: 1-26. PMID: 24654857, PMCID: PMC4360991, DOI: 10.1111/nyas.12388.Peer-Reviewed Original Research
2011
Cognitive control and the dopamine D2‐like receptor: a dimensional understanding of addiction
Groman SM, Jentsch JD. Cognitive control and the dopamine D2‐like receptor: a dimensional understanding of addiction. Depression And Anxiety 2011, 29: 295-306. PMID: 22147558, DOI: 10.1002/da.20897.Peer-Reviewed Original ResearchMeSH KeywordsBehavior, AddictiveBiomarkersDopamineHumansImpulsive BehaviorInhibition, PsychologicalMental DisordersReceptors, Dopamine D2ConceptsCognitive controlCognitive control abilitiesSubstantial psychosocial impairmentCognitive processesPsychosocial impairmentDimensional understandingCognitive dysfunctionControl abilityCategorical diagnosesPsychiatric conditionsParticular dimensionAddictionPsychiatric disordersImpairmentDisordersDA receptor functionPoint of convergenceCrucial dimensionDimensional natureReceptor transmissionDopamine D2-like receptorsFeelingsSymptomatologyTreatment responseD2-like receptors
2008
Poor response inhibition: At the nexus between substance abuse and attention deficit/hyperactivity disorder
Groman SM, James AS, Jentsch JD. Poor response inhibition: At the nexus between substance abuse and attention deficit/hyperactivity disorder. Neuroscience & Biobehavioral Reviews 2008, 33: 690-698. PMID: 18789354, PMCID: PMC2728075, DOI: 10.1016/j.neubiorev.2008.08.008.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderSubstance abuseSubstance abuse/dependenceHyperactivity disorderAnimal model studiesAbuse/dependenceAttention-deficit/hyperactivity disorderDeficit/hyperactivity disorderResponse inhibition functionDeficit hyperactivity disorderUltimate progressionDependence disordersUnderlying biological mechanismsAnimal modelsBehavioral impairmentsCingulate cortexDisordersMultiple causesExhibit deficitsADHD-like traitsDrug takingResponse inhibitionBiological mechanismsImpairmentNeural level
2007
Dimensions of Impulsivity Are Associated with Poor Spatial Working Memory Performance in Monkeys
James AS, Groman SM, Seu E, Jorgensen M, Fairbanks LA, Jentsch JD. Dimensions of Impulsivity Are Associated with Poor Spatial Working Memory Performance in Monkeys. Journal Of Neuroscience 2007, 27: 14358-14364. PMID: 18160643, PMCID: PMC6673444, DOI: 10.1523/jneurosci.4508-07.2007.Peer-Reviewed Original ResearchConceptsDimensions of impulsivityMemory performanceNonsocial stimuliResponse taskImpulsive behaviorDRD4 genotypeAttention-deficit/hyperactivity disorderDeficit/hyperactivity disorderSpatial Working Memory PerformanceHigh impulsive animalsWorking Memory PerformanceDelayed response taskDimensions of temperamentLow impulsive subjectsDRD4 allelesNeurocognitive endophenotypesDopamine D4 receptor geneHyperactivity disorderD4 receptor geneDimensional phenotypesCorrect responsesDelay versionImpulsivityCeiling levelImpulsive approach