1998
Safety and efficacy of isolated perfusion of extremities for recurrent tumor in elderly patients
Ariyan S, Poo W. Safety and efficacy of isolated perfusion of extremities for recurrent tumor in elderly patients. Surgery 1998, 123: 335-343. PMID: 9526527, DOI: 10.1016/s0039-6060(98)70188-6.Peer-Reviewed Original ResearchConceptsElderly patientsYounger patientsIsolated perfusionMeaningful disease controlRegional isolated perfusionEvidence of diseaseHigh-dose chemotherapySeries of patientsIsolated limb perfusionMajor surgical proceduresNumber of patientsDisease-free controlsYears of ageSalvage of limbsSignificant palliationThird perfusionAggressive treatmentDose chemotherapyOlder patientsRecurrent diseaseSurvival benefitTransit diseaseSerious complicationsRecurrent tumorsLimb perfusion
1997
Regional Isolated Perfusion of Extremities for Melanoma: A 20-Year Experience with Drugs Other than L-Phenylalanine Mustard
Ariyan S, Poo W, Bolognia J. Regional Isolated Perfusion of Extremities for Melanoma: A 20-Year Experience with Drugs Other than L-Phenylalanine Mustard. Plastic & Reconstructive Surgery 1997, 99: 1023-1029. PMID: 9091898, DOI: 10.1097/00006534-199704000-00016.Peer-Reviewed Original ResearchConceptsL-phenylalanine mustardRegional isolated perfusionIsolated limb perfusionIsolated perfusionLimb perfusionUpper extremityLower extremitiesTherapeutic isolated limb perfusionNonfatal pulmonary embolusRegional treatment modalityEvidence of diseaseHigh-dose chemotherapyHigh-risk melanomaNumber of patientsDifficult management problemDisease-free controlsTechnique of perfusionLimb recurrenceMeaningful palliationRepeat perfusionsAggressive treatmentPulmonary emboliDose chemotherapyRecurrent melanomaSerious complications
1984
Regional isolated perfusion of high risk melanoma of the extremities with imidazole carboxamide.
Ariyan S, Mitchell M, Kirkwood J. Regional isolated perfusion of high risk melanoma of the extremities with imidazole carboxamide. Journal Of The American College Of Surgeons 1984, 158: 238-42. PMID: 6701736.Peer-Reviewed Original ResearchConceptsRegional isolated perfusionIntransit metastasesIsolated perfusionSerum glutamic-oxalacetic transaminase levelFirst postoperative dayGlutamic oxalacetic transaminase levelHigh-risk melanomaTransaminase levelsPostoperative daySubcutaneous metastasesFourth patientNew lesionsFifth patientRisk melanomaImidazole carboxamidePatientsPerfused extremitySymptoms of toxicityValuable drugMetastasisExtremitiesMelanomaPerfusionMonthsDecarbazine