Song Chen, PhD
Associate Research Scientist in PharmacologyCards
About
Research
Publications
2026
PIP4K2A depletion suppresses AKT signaling and enhances chemotherapy sensitivity in T-cell lymphoblastic lymphoma cells
Chen S, He Z, Ha Y. PIP4K2A depletion suppresses AKT signaling and enhances chemotherapy sensitivity in T-cell lymphoblastic lymphoma cells. Biochemical And Biophysical Research Communications 2026, 832: 154404. PMID: 42570494, PMCID: PMC13528604, DOI: 10.1016/j.bbrc.2026.154404.Peer-Reviewed Original ResearchStructural basis for high-affinity inhibitor binding to lipid kinases PIP4K2A and PIP4K2B
He Z, Chen S, Micheli F, Cianciulli A, Beato C, Ellman J, Ha Y. Structural basis for high-affinity inhibitor binding to lipid kinases PIP4K2A and PIP4K2B. Acta Crystallographica Section D, Structural Biology 2026, 82: 646-654. PMID: 42117906, PMCID: PMC13224930, DOI: 10.1107/s2059798326003773.Peer-Reviewed Original ResearchPIP4K2A/2B inhibitor suppresses tumor growth in a xenograft model of NSCLC
He Z, Chen S, Bosenberg M, Muthusamy V, Xi Y, Wang H, Micheli F, Cianciulli A, Beato C, Van Zandt M, Ellman J, Ha Y. PIP4K2A/2B inhibitor suppresses tumor growth in a xenograft model of NSCLC. IScience 2026, 29: 115952. PMID: 42205699, PMCID: PMC13206749, DOI: 10.1016/j.isci.2026.115952.Peer-Reviewed Original Research
2024
LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments
Tang W, Luan Y, Yuan Q, Li A, Chen S, Menacherry S, Young L, Wu D. LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments. Nature Communications 2024, 15: 3068. PMID: 38594269, PMCID: PMC11004178, DOI: 10.1038/s41467-024-47262-z.Peer-Reviewed Original Research
2012
Structural characterization of full-length NSF and 20S particles
Chang L, Chen S, Liu C, Pan X, Jiang J, Bai X, Xie X, Wang H, Sui S. Structural characterization of full-length NSF and 20S particles. Nature Structural & Molecular Biology 2012, 19: 268-275. PMID: 22307055, DOI: 10.1038/nsmb.2237.Peer-Reviewed Original Research
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