2024
Association Between Restricting Symptoms and Disability After Critical Illness Among Older Adults.
Jain S, Han L, Gahbauer E, Leo-Summers L, Feder S, Ferrante L, Gill T. Association Between Restricting Symptoms and Disability After Critical Illness Among Older Adults. Critical Care Medicine 2024, 52: 1816-1827. PMID: 39298623, DOI: 10.1097/ccm.0000000000006427.Peer-Reviewed Original ResearchActivities of daily livingAssociated with increased disabilityDaily livingOlder adultsRestricting symptomsInstrumental activities of daily livingCommunity-living older adultsICU hospitalizationMultivariable Poisson regression modelsCommunity-living adultsOlder ICU survivorsAge of participantsPoisson regression modelsSurvive critical illnessCritical illnessQuality of lifeInstrumental activitiesICU survivorsProspective longitudinal studyLength of stayPost-ICUIncreased disabilityMonthly interviewsICU length of stayPre-ICUTrends in use of intensive care during hospitalizations at the end‐of‐life among older adults with advanced cancer
Jain S, Long J, Rao V, Law A, Walkey A, Prsic E, Lindenauer P, Krumholz H, Gross C. Trends in use of intensive care during hospitalizations at the end‐of‐life among older adults with advanced cancer. Journal Of The American Geriatrics Society 2024 PMID: 39090970, DOI: 10.1111/jgs.19119.Peer-Reviewed Original ResearchEnd-of-life hospitalizationsLife-sustaining treatmentEnd-of-lifeIntensity of careIn-hospital deathOlder adultsIntensive care unitAdvanced cancerRisk-adjusted hospitalEvaluate trendsIncreased intensity of careIntensive care unit useSEER-Medicare dataIntensive care unit careMultinomial regression modelsYear of diagnosisIntensive careHospital categoryMedicare beneficiariesSEER-MedicareHospitalization ratesCareCancer characteristicsNoninvasive ventilationHospitalSocial Determinants of Health and Delivery of Rehabilitation to Older Adults During ICU Hospitalization
Jain S, Murphy T, Falvey J, Leo-Summers L, O’Leary J, Zang E, Gill T, Krumholz H, Ferrante L. Social Determinants of Health and Delivery of Rehabilitation to Older Adults During ICU Hospitalization. JAMA Network Open 2024, 7: e2410713. PMID: 38728030, PMCID: PMC11087837, DOI: 10.1001/jamanetworkopen.2024.10713.Peer-Reviewed Original ResearchConceptsSocial determinants of healthDeterminants of healthOccupational therapyPhysical therapyOlder adultsRural residentsIntensive care unit hospitalizationRehabilitation deliveryIntensive care unitSocial determinantsSocioeconomic disadvantageNational Health and Aging Trends StudyDelivery of physical therapyIllness hospitalizationFactors associated with lower oddsDelivery of rehabilitationIn-hospital rehabilitationMitigate functional declineMedicaid eligibilityBurden of disabilityHigh school educationDual MedicareTrends StudyMedicare claimsLength of staySurvival, Function, and Cognition After Hospitalization in Long-Term Acute Care Hospitals
Jain S, Gan S, Nguyen O, Sudore R, Steinman M, Covinsky K, Makam A. Survival, Function, and Cognition After Hospitalization in Long-Term Acute Care Hospitals. JAMA Network Open 2024, 7: e2413309. PMID: 38805226, PMCID: PMC11134219, DOI: 10.1001/jamanetworkopen.2024.13309.Peer-Reviewed Original ResearchConceptsHealth and Retirement StudyLong-term acute care hospitalHealth and Retirement Study interviewsActivities of daily livingAcute care hospitalsOlder adultsMiddle-agedCognitive statusLong-term acute care hospital admissionCare hospitalCohort studyAcute illnessAssociated with lower riskIncreased likelihood of deathAdverse outcomesLikelihood of deathMultivariate logistic regressionReceipt of mechanical ventilationSevere impairmentDaily livingRetirement StudyRetrospective cohort studyMedicare claimsLee index scoresMain OutcomesHospital Variation in Delivery of Skilled Rehabilitation to Mechanically Ventilated Older Adults With Acute Respiratory Failure
Jimenez Ceja J, Zhang L, Lin Z, Walkey A, Krumholz H, Jain S. Hospital Variation in Delivery of Skilled Rehabilitation to Mechanically Ventilated Older Adults With Acute Respiratory Failure. 2024, a1096-a1096. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a1096.Peer-Reviewed Original Research
2023
Social Vulnerability and Delivery of In-hospital Rehabilitation Services to Older Adults With Critical Illness
Jain S, Murphy T, O'Leary Jr J, Leo-Summers L, Zang E, Falvey J, Gill T, Krumholz H, Ferrante L. Social Vulnerability and Delivery of In-hospital Rehabilitation Services to Older Adults With Critical Illness. 2023, a2889-a2889. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2889.Peer-Reviewed Original ResearchPreexisting Care Needs and Long-Term Outcomes After Mechanical Ventilation: Are We Any Closer to Informing Treatment Choices for Older Adults?*
Jain S. Preexisting Care Needs and Long-Term Outcomes After Mechanical Ventilation: Are We Any Closer to Informing Treatment Choices for Older Adults?*. Critical Care Medicine 2023, 51: 683-685. PMID: 37052439, DOI: 10.1097/ccm.0000000000005827.Peer-Reviewed Original Research
2022
Clin‐STAR corner: Recent practice‐changing studies at the interface of pulmonary and critical care medicine and geriatrics
Jain S, Witt L, Ferrante L. Clin‐STAR corner: Recent practice‐changing studies at the interface of pulmonary and critical care medicine and geriatrics. Journal Of The American Geriatrics Society 2022, 71: 705-710. PMID: 36536494, PMCID: PMC10023292, DOI: 10.1111/jgs.18196.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCritical care medicineCritical illnessPulmonary diseaseLung diseaseCare medicineRecent practice-changing clinical trialsChronic obstructive pulmonary diseaseOlder adultsAcute respiratory failurePractice-changing clinical trialsChronic lung diseaseChronic pulmonary diseaseObstructive pulmonary diseaseInterstitial lung diseasePractice-changing studiesGreater side effectsRespiratory failureAdverse outcomesClinical trialsObservational studySide effectsDiseaseIllnessAdultsMedicine
2021
Emergency department visits for emergent conditions among older adults during the COVID‐19 pandemic
Janke AT, Jain S, Hwang U, Rosenberg M, Biese K, Schneider S, Goyal P, Venkatesh AK. Emergency department visits for emergent conditions among older adults during the COVID‐19 pandemic. Journal Of The American Geriatrics Society 2021, 69: 1713-1721. PMID: 33955546, PMCID: PMC8242842, DOI: 10.1111/jgs.17227.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionED visit countsOlder adultsHip fractureExcess mortalityEmergent conditionsED sitesVisit countsEmergency department visitsIncident rate ratiosNational clinical quality registryAge categoriesClinical quality registryEarly pandemic periodCOVID-19 pandemicPandemic periodPoisson regression modelsPre-pandemic periodED visitsYounger patientsDepartment visitsPoor outcomeEmergency departmentMyocardial infarctionED diagnosis