2024
Biomarker Panels for Predicting Progression of Kidney Disease in Acute Kidney Injury Survivors.
Menez S, Kerr K, Cheng S, Hu D, Thiessen-Philbrook H, Moledina D, Mansour S, Go A, Ikizler T, Kaufman J, Kimmel P, Himmelfarb J, Coca S, Parikh C. Biomarker Panels for Predicting Progression of Kidney Disease in Acute Kidney Injury Survivors. Clinical Journal Of The American Society Of Nephrology 2024 PMID: 39671257, DOI: 10.2215/cjn.0000000622.Peer-Reviewed Original ResearchAcute kidney injurySoluble tumor necrosis factor receptor 1End-stage kidney diseaseChronic kidney diseaseKidney diseaseFollow-upPost-AKI careDevelopment of end-stage kidney diseaseKidney-specific outcomesYears of follow-upCombination of clinical variablesReceiver-operating characteristic curveTumor necrosis factor receptor 1Progression of kidney diseaseSequelae of acute kidney injuryAdverse kidney eventsAge of study participantsAcute kidney injury survivorsDiuretic useEGFR declineKidney disease riskKidney eventsAKI patientsKidney injuryPost-discharge follow-up
2023
Integrated Analysis of Blood and Urine Biomarkers to Identify Acute Kidney Injury Subphenotypes and Associations With Long-term Outcomes
Bhatraju P, Prince D, Mansour S, Ikizler T, Siew E, Chinchilli V, Garg A, Go A, Kaufman J, Kimmel P, Coca S, Parikh C, Wurfel M, Himmelfarb J. Integrated Analysis of Blood and Urine Biomarkers to Identify Acute Kidney Injury Subphenotypes and Associations With Long-term Outcomes. American Journal Of Kidney Diseases 2023, 82: 311-321.e1. PMID: 37178093, PMCID: PMC10523857, DOI: 10.1053/j.ajkd.2023.01.449.Peer-Reviewed Original ResearchConceptsMajor adverse kidney eventsLong-term outcomesAKI subphenotypesKidney injuryClinical outcomesUrinary biomarkersHigh riskChronic kidney disease progressionLong-term clinical outcomesCox proportional hazards modelAdverse kidney eventsLong-term sequalaeHospital-level factorsKidney disease progressionChronic kidney diseaseKaplan-Meier curvesSerum creatinine concentrationEpithelial cell injuryHeterogeneous clinical syndromeProportional hazards modelLong-term riskAKI patientsAKI subgroupKDIGO stageMedian follow