2016
A Sawtooth Pattern of Cadherin 2 Stability Mechanically Regulates Somite Morphogenesis
McMillen P, Chatti V, Jülich D, Holley SA. A Sawtooth Pattern of Cadherin 2 Stability Mechanically Regulates Somite Morphogenesis. Current Biology 2016, 26: 542-549. PMID: 26853361, PMCID: PMC4822709, DOI: 10.1016/j.cub.2015.12.055.Peer-Reviewed Original ResearchConceptsECM assemblyGenetic mosaicsPosterior somitesDifferential cadherin expressionExtracellular matrixCell-ECM adhesionFN matrix assemblyBoundary formationVertebrate gastrulationSomite boundariesSomite morphogenesisCytoskeletal contractilityParaxial mesodermEmbryonic precursorsCDH activityMatrix assemblyCadherin expressionCDH2SomitesTissue boundariesIntegrin α5SomitogenesisCell sortingCell aggregatesAssembly
2009
Control of extracellular matrix assembly along tissue boundaries via Integrin and Eph/Ephrin signaling
Jülich D, Mould AP, Koper E, Holley SA. Control of extracellular matrix assembly along tissue boundaries via Integrin and Eph/Ephrin signaling. Development 2009, 136: 2913-2921. PMID: 19641014, DOI: 10.1242/dev.038935.Peer-Reviewed Original Research
2000
Control of her1 expression during zebrafish somitogenesis by a Delta-dependent oscillator and an independent wave-front activity
Holley S, Geisler R, Nüsslein-Volhard C. Control of her1 expression during zebrafish somitogenesis by a Delta-dependent oscillator and an independent wave-front activity. Genes & Development 2000, 14: 1678-1690. PMID: 10887161, PMCID: PMC316735, DOI: 10.1101/gad.14.13.1678.Peer-Reviewed Original ResearchConceptsAnterior presomitic mesodermPresomitic mesodermGene expressionNotch pathwayHER1 expressionZebrafish genesZebrafish somitogenesisEmbryos mutantSomite morphogenesisMolecular clockExpression patternsExpression de novoExpression oscillatesNotch ligandsPathway upstreamSomitogenesisBorder formationConsecutive somitesDe novoSomitesExpressionWave-front modelPathwayClockHER1