2022
Nanoparticle-based drug delivery for the treatment of traumatic brain injury
Mohammed F, Omay S, Sheth K, Zhou J. Nanoparticle-based drug delivery for the treatment of traumatic brain injury. Expert Opinion On Drug Delivery 2022, 20: 55-73. PMID: 36420918, PMCID: PMC9983310, DOI: 10.1080/17425247.2023.2152001.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryBrain injurySecondary outcomesClinical trialsPathophysiology of TBIPhase III clinical trialsPhase II clinical trialClinical management strategiesSite of injuryOff-target toxicityPharmacological treatmentBrain penetrationLow off-target toxicityExperimental animalsInjuryChronic timescalesDosage thresholdDrug deliveryTrialsDrug targetingOutcomesTreatmentDeliveryPathophysiology
2012
Low-Grade Gliomas When and How to Treat
Omay SB, Piepmeier JM, Knisely JP. Low-Grade Gliomas When and How to Treat. Hematology/Oncology Clinics Of North America 2012, 26: 797-809. PMID: 22794284, DOI: 10.1016/j.hoc.2012.05.001.Peer-Reviewed Original ResearchConceptsSurgical resectionLow-grade gliomasPatient-specific variablesSame imaging techniqueRadiotherapeutic managementUncommon tumorClinical trialsOperative techniqueHistopathologic characterizationGrade gliomasOptimal managementAdditional studiesGliomasResectionAdequate samplesImaging techniquesPatientsPrognosisManagementTumorsTrials
2011
Primary Central Nervous System Vasculitis Presenting as Spinal Subdural Hematoma
Fu M, Omay SB, Morgan J, Kelley B, Abbed K, Bulsara KR. Primary Central Nervous System Vasculitis Presenting as Spinal Subdural Hematoma. World Neurosurgery 2011, 78: 192.e5-192.e8. PMID: 22120304, DOI: 10.1016/j.wneu.2011.07.043.Peer-Reviewed Original ResearchConceptsPrimary central nervous system vasculitisSpinal subdural hematomaCentral nervous systemSpinal cord vasculitisSubdural hematomaNervous systemAcute spinal subdural hematomaCentral nervous system vasculitisPrimary central nervous systemAcute hypertensive eventSystemic inflammatory disorderVascular inflammatory conditionsMagnetic resonance imagingEmergent laminectomyHypertensive eventsCerebral edemaVasculitic processIntracranial vasculitisInflammatory disordersTypical presentationInflammatory conditionsSpinal cordUnreported etiologyDifferential diagnosisVasculitis
2009
Unusual presentations of nervous system infection by Cryptococcus neoformans
Searls D, Sico JJ, Omay S, Bannykh S, Kuohung V, Baehring J. Unusual presentations of nervous system infection by Cryptococcus neoformans. Clinical Neurology And Neurosurgery 2009, 111: 638-642. PMID: 19541406, DOI: 10.1016/j.clineuro.2009.05.007.Peer-Reviewed Original ResearchConceptsNervous system infectionHuman immunodeficiency virusSystem infectionCryptococcal meningitisNeurological manifestationsCryptococcus neoformansRecurrent cerebral infarctionSevere neurological disabilityC. neoformans infectionUnusual clinical presentationUnusual neurological manifestationsDetailed clinical descriptionMagnetic resonance imagingOphthalmic zosterCryptococcal infectionCerebral infarctionImmunocompetent patientsNeoformans infectionNeurological disabilityClinical presentationHodgkin's diseaseImmunodeficiency syndromeImmunocompetent hostsImmunodeficiency virusCSF analysis