2024
Association between psoriasis and obsessive-compulsive disorder: a case-control study in the All of Us research program
Craver A, Chen G, Fan R, Levey D, Cohen J. Association between psoriasis and obsessive-compulsive disorder: a case-control study in the All of Us research program. Archives Of Dermatological Research 2024, 316: 280. PMID: 38796663, DOI: 10.1007/s00403-024-03112-y.Peer-Reviewed Original Research
2023
Psoriasis associated with asthma and allergic rhinitis: a US-based cross-sectional study using the All of US Research Program
Joel M, Fan R, Damsky W, Cohen J. Psoriasis associated with asthma and allergic rhinitis: a US-based cross-sectional study using the All of US Research Program. Archives Of Dermatological Research 2023, 315: 1823-1826. PMID: 36707438, DOI: 10.1007/s00403-023-02539-z.Peer-Reviewed Original ResearchConceptsAllergic rhinitisUS adultsUs Research ProgramCommon chronic inflammatory diseaseMultivariable logistic regression modelNationwide longitudinal cohortImmunopathogenesis of psoriasisBody mass indexChronic inflammatory diseaseCases of asthmaCross-sectional studyLogistic regression modelsMultivariable analysisSmoking statusMass indexInflammatory pathwaysSubgroup analysisInflammatory diseasesLongitudinal cohortHigh prevalenceAsthmaPsoriasisPotential associationDiverse cohortSociodemographic variables
2022
The association of atopic dermatitis and chronic rhinosinusitis in adults: a cross‐sectional study using the All of Us research program
Hodelin C, Fan R, Damsky W, Cohen J. The association of atopic dermatitis and chronic rhinosinusitis in adults: a cross‐sectional study using the All of Us research program. International Journal Of Dermatology 2022, 62: e430-e431. PMID: 36468789, DOI: 10.1111/ijd.16544.Peer-Reviewed Original ResearchMigraine among adults with atopic dermatitis: a cross-sectional study in the All of Us research programme
Fan R, Leasure A, Damsky W, Cohen J. Migraine among adults with atopic dermatitis: a cross-sectional study in the All of Us research programme. Clinical And Experimental Dermatology 2022, 48: 24-26. PMID: 36669173, DOI: 10.1093/ced/llac004.Peer-Reviewed Original ResearchAlcohol use disorder among adults with atopic dermatitis: A case-control study in the All of Us research program
Fan R, Leasure AC, Damsky W, Cohen JM. Alcohol use disorder among adults with atopic dermatitis: A case-control study in the All of Us research program. Journal Of The American Academy Of Dermatology 2022, 87: 1378-1380. PMID: 36152694, DOI: 10.1016/j.jaad.2022.09.015.Peer-Reviewed Original ResearchAssociation of atopic dermatitis with attention-deficit hyperactivity disorder among US adults in the “All of Us” research program: A case-control study
Fan R, Leasure AC, Damsky W, Cohen JM. Association of atopic dermatitis with attention-deficit hyperactivity disorder among US adults in the “All of Us” research program: A case-control study. Journal Of The American Academy Of Dermatology 2022, 87: 691-692. PMID: 35283246, DOI: 10.1016/j.jaad.2022.03.014.Peer-Reviewed Original Research
2019
Clinical Implications of Plasma-Based Genotyping With the Delivery of Personalized Therapy in Metastatic Non–Small Cell Lung Cancer
Aggarwal C, Thompson J, Black T, Katz S, Fan R, Yee S, Chien A, Evans T, Bauml J, Alley E, Ciunci C, Berman A, Cohen R, Lieberman D, Majmundar K, Savitch S, Morrissette J, Hwang W, Elenitoba-Johnson K, Langer C, Carpenter E. Clinical Implications of Plasma-Based Genotyping With the Delivery of Personalized Therapy in Metastatic Non–Small Cell Lung Cancer. JAMA Oncology 2019, 5: 173-180. PMID: 30325992, PMCID: PMC6396811, DOI: 10.1001/jamaoncol.2018.4305.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkers, TumorCarcinoma, Non-Small-Cell LungClinical Decision-MakingDNA Mutational AnalysisFemaleGenetic Predisposition to DiseaseHumansLung NeoplasmsMaleMiddle AgedMutationPatient SelectionPhenotypePrecision MedicinePredictive Value of TestsPrognosisProspective StudiesConceptsNon-small cell lung cancerTissue next-generation sequencingMetastatic non-small cell lung cancerCell lung cancerTargetable mutationsNext-generation sequencingLung cancerPlasma testingStage IV non-small cell lung cancerAllele fractionNGS testingClinical implicationsPlasma next-generation sequencingPersonalized therapyReal-world clinical settingProspective cohort studyResponse Evaluation CriteriaRoutine clinical managementNumber of patientsSolid Tumors responseDNA next-generation sequencingStable diseaseMutation allele fractionCohort studyPartial response
2018
Measurement and immunophenotyping of pleural fluid EpCAM-positive cells and clusters for the management of non-small cell lung cancer patients
Thompson J, Fan R, Black T, Yu G, Savitch S, Chien A, Yee S, Sen M, Hwang W, Katz S, Feldman M, Vachani A, Carpenter E. Measurement and immunophenotyping of pleural fluid EpCAM-positive cells and clusters for the management of non-small cell lung cancer patients. Lung Cancer 2018, 127: 25-33. PMID: 30642547, PMCID: PMC6657687, DOI: 10.1016/j.lungcan.2018.11.020.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerMalignant pleural effusionPleural fluid samplesEpCAM-positive cellsPD-L1 expressionNSCLC patientsOverall survivalPrognostic informationNon-small cell lung cancer patientsFluid samplesCell lung cancer patientsCox proportional hazards modelInferior overall survivalKaplan-Meier methodNon-malignant groupCell lung cancerLung cancer patientsProportional hazards modelPleural fluid specimensCommon complicationPD-L1Pleural effusionCurrent gold standardCancer patientsLung cancer
2016
Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA
Thompson J, Yee S, Troxel A, Savitch S, Fan R, Balli D, Lieberman D, Morrissette J, Evans T, Bauml J, Aggarwal C, Kosteva J, Alley E, Ciunci C, Cohen R, Bagley S, Stonehouse-Lee S, Sherry V, Gilbert E, Langer C, Vachani A, Carpenter E. Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA. Clinical Cancer Research 2016, 22: 5772-5782. PMID: 27601595, PMCID: PMC5448134, DOI: 10.1158/1078-0432.ccr-16-1231.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerCtDNA next-generation sequencingResistance mutationsNext-generation sequencingTissue sequencingAdvanced non-small cell lung cancerActionable EGFR mutationsCell lung cancerProgressive diseaseConsecutive patientsCtDNA sequencingTargetable driversLung cancerClinical trialsDisease progressionEGFR mutationsUltra-deep sequencingPatient managementExperimental therapiesTumor genotypingCtDNA samplesTissue biopsiesPatientsAccurate diagnosisBlood collection