2000
The Toll receptor family and microbial recognition
Medzhitov R, Janeway C. The Toll receptor family and microbial recognition. Trends In Microbiology 2000, 8: 452-456. PMID: 11044679, DOI: 10.1016/s0966-842x(00)01845-x.Peer-Reviewed Original Research
1999
The Toll-receptor family and control of innate immunity
Kopp E, Medzhitov R. The Toll-receptor family and control of innate immunity. Current Opinion In Immunology 1999, 11: 13-18. PMID: 10047546, DOI: 10.1016/s0952-7915(99)80003-x.Peer-Reviewed Original ResearchConceptsInducible immune response genesToll receptor familyToll receptorTransduction pathwaysImmune response genesHost defense systemInnate immune recognitionMicrobial pathogensGermline-encoded receptorsNuclear factor-kappaBMolecular patternsDefense systemInnate immunityFactor-kappaBImmune recognitionPathwayReceptorsInsectsMammalsGenesPlantsPathogensExpressionKappaBFamily