2003
Toll-like receptors and their role in experimental models of microbial infection
Qureshi S, Medzhitov R. Toll-like receptors and their role in experimental models of microbial infection. Genes & Immunity 2003, 4: 87-94. PMID: 12618855, DOI: 10.1038/sj.gene.6363937.Peer-Reviewed Original ResearchConceptsImmune systemHost defenseToll-like receptor (TLR) familyExperimental modelTLR-deficient miceMicrobial infectionsAdaptive immune responsesToll-like receptorsEffective host defenseLimited human studiesInnate immune systemAdaptive immune systemPrompt recognitionImmune responseHuman studiesInnate immunityInfectious threatsInfectionReceptor familyAntimicrobial effectorsContainment measuresPathogen recognitionConstant surveillancePathogensActivation
1999
Innate immunity: Lipoproteins take their Toll on the host
Janeway C, Medzhitov R. Innate immunity: Lipoproteins take their Toll on the host. Current Biology 1999, 9: r879-r882. PMID: 10607553, DOI: 10.1016/s0960-9822(00)80073-1.Peer-Reviewed Original Research
1997
Innate immunity: impact on the adaptive immune response
Medzhitov R, Janeway C. Innate immunity: impact on the adaptive immune response. Current Opinion In Immunology 1997, 9: 4-9. PMID: 9039775, DOI: 10.1016/s0952-7915(97)80152-5.Peer-Reviewed Original Research