Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation
Hargreaves D, Horng T, Medzhitov R. Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation. Journal Of End-to-End-testing 2009, 138: 129-145. DOI: 10.1016/s9999-9994(09)20368-0.Peer-Reviewed Original ResearchTranscriptional elongationP-TEFbSignal-dependent recruitmentProtein-coding transcriptsRNA polymerase IIInducible transcriptional programSecondary response genesInducible gene expressionNew protein synthesisMultiple cell typesCorepressor complexChromatin remodelingHistone modificationsPolymerase IIPol IIMRNA processingTranscriptional programsProtein BRD4Unspliced transcriptsKinetics of expressionResponse genesUnique regulationGene expressionEssential functionsProtein synthesis