2009
Heart-brain interactions in mental stress-induced myocardial ischemia
Soufer R, Jain H, Yoon AJ. Heart-brain interactions in mental stress-induced myocardial ischemia. Current Cardiology Reports 2009, 11: 133-140. PMID: 19236829, PMCID: PMC3726062, DOI: 10.1007/s11886-009-0020-1.Peer-Reviewed Original ResearchConceptsMental stress ischemiaStress ischemiaMyocardial ischemiaMental stress-induced myocardial ischemiaStress-induced myocardial ischemiaCoronary artery diseaseCentral nervous systemHeart-brain interactionsArtery diseasePoor prognosisAutonomic balancePathophysiologic underpinningsTreatment strategiesNervous systemIschemiaPsychosocial stressBiobehavioral aspectsBiobehavioral modelBiologic consequencesSensory inputBiologic processesBrainEmotional provocationPatientsPrognosis
2000
Persistent Changes in Myocardial Glucose Metabolism In Vivo During Reperfusion of a Limited-Duration Coronary Occlusion
McNulty P, Jagasia D, Cline G, Ng C, Whiting J, Garg P, Shulman G, Soufer R. Persistent Changes in Myocardial Glucose Metabolism In Vivo During Reperfusion of a Limited-Duration Coronary Occlusion. Circulation 2000, 101: 917-922. PMID: 10694532, DOI: 10.1161/01.cir.101.8.917.Peer-Reviewed Original ResearchConceptsCoronary occlusionGlucose metabolismPostischemic stunningAnterolateral left ventricleHeart glucose metabolismCoronary artery occlusionRegional glucose metabolismMyocardial glucose metabolismRegional myocardial ischemiaRegional mechanical functionRapid reperfusionReversible coronary occlusionArtery occlusionMyocardial ischemiaIntact ratsPreferential shuntingBlood flowReperfusionTracer uptakeLeft ventricleGlycogen depletionMetabolic signaturesOcclusionPersistent changesSustained changes
1998
Myocardial viability: Seeking relevance and redefinition
Arrighi J, Soufer R. Myocardial viability: Seeking relevance and redefinition. Journal Of Nuclear Cardiology 1998, 5: 629-633. PMID: 9869486, DOI: 10.1016/s1071-3581(98)90118-0.Peer-Reviewed Original ResearchEffect of hyperinsulinemia on myocardial fluorine-18-FDG uptake.
Ng C, Soufer R, McNulty P. Effect of hyperinsulinemia on myocardial fluorine-18-FDG uptake. Journal Of Nuclear Medicine 1998, 39: 379-83. PMID: 9529278.Peer-Reviewed Original ResearchConceptsCoronary sinus blood samplesIschemic heart diseasePrevious myocardial infarctionCoronary sinus catheterizationEffect of insulinLeft anteriorMale patientsMyocardial infarctionHeart diseaseFDG injectionVascular bedBlood samplesAwake statePatientsGlucose uptakeMyocardial kineticsFDGCatheterizationInfarctionDiabetesBolusAnteriorInsulinDisease
1996
Autoregulation of myocardial glycogen concentration during intermittent hypoxia
McNulty P, Ng C, Liu W, Jagasia D, Letsou G, Baldwin J, Soufer R. Autoregulation of myocardial glycogen concentration during intermittent hypoxia. American Journal Of Physiology 1996, 271: r311-r319. PMID: 8770128, DOI: 10.1152/ajpregu.1996.271.2.r311.Peer-Reviewed Original Research
1995
Kinetic analysis of technetium-99m-labeled nitroimidazole (BMS-181321) as a tracer of myocardial hypoxia.
Ng C, Sinusas A, Zaret B, Soufer R. Kinetic analysis of technetium-99m-labeled nitroimidazole (BMS-181321) as a tracer of myocardial hypoxia. Circulation 1995, 92: 1261-8. PMID: 7648674, DOI: 10.1161/01.cir.92.5.1261.Peer-Reviewed Original ResearchRelationship between reverse redistribution on planar thallium scintigraphy and regional myocardial viability: a correlative PET study.
Soufer R, Dey H, Lawson A, Wackers F, Zaret B. Relationship between reverse redistribution on planar thallium scintigraphy and regional myocardial viability: a correlative PET study. Journal Of Nuclear Medicine 1995, 36: 180-7. PMID: 7830110.Peer-Reviewed Original ResearchConceptsPlanar thallium scintigraphyCardiac eventsThallium scintigraphyReverse redistributionChronic coronary artery diseasePET viabilityAbnormal regional wall motionPlanar thallium imagesMyocardial Infarction trialPercent of patientsFuture cardiac eventsFuture cardiovascular eventsCoronary artery diseaseFavorable clinical outcomeMyocardial metabolic activityRegional wall motion analysisRegional wall motionPercent of segmentsWall motion analysisPET criteriaCardiovascular eventsReperfusion therapyArtery diseaseClinical outcomesPrognostic value
1991
Thallium-201 for assessment of myocardial viability: Quantitative comparison of 24-hour redistribution imaging with imaging after reinjection at rest
Kayden D, Sigal S, Soufer R, Mattera J, Zaret B, Wackers F. Thallium-201 for assessment of myocardial viability: Quantitative comparison of 24-hour redistribution imaging with imaging after reinjection at rest. Journal Of The American College Of Cardiology 1991, 18: 1480-1486. PMID: 1939949, DOI: 10.1016/0735-1097(91)90678-3.Peer-Reviewed Original ResearchConceptsInjection of thalliumRedistribution imagesDefect reversibilityThallium-201 reinjectionThallium-201 defectsLate redistribution imagingPoor quality studiesDiagnostic informationClinical variablesRedistribution imagingThallium defectsThallium imagesMyocardial viabilityReversible defectsStress imagingThallium-201PatientsBetter diagnostic informationStress testingExercisePresent studyQuality studiesInjectionLate redistributionReinjection