2002
Beta IV Spectrin in Normal and Cancer Breast Cells
De Camilli P. Beta IV Spectrin in Normal and Cancer Breast Cells. 2002 DOI: 10.21236/ada418127.Peer-Reviewed Original ResearchBeta IV spectrinBreast cancerLower motor neuron syndromeMotor neuron syndromeNervous system functionSignificant neurological defectsAutoimmune impairmentParaneoplastic conditionNeuronal antigensNovel autoantigenAutoimmune responseCancer immunotherapyCancer patientsPathogenetic mechanismsNeurological conditionsSuch antibodiesSide effectsCancer tissuesNeurological defectsMutant miceAxonal physiologyBreast cellsCancerCancer cellsDiagnostic tool
2000
Autoimmunity to Gephyrin in Stiff-Man Syndrome
Butler M, Hayashi A, Ohkoshi N, Villmann C, Becker C, Feng G, De Camilli P, Solimena M. Autoimmunity to Gephyrin in Stiff-Man Syndrome. Neuron 2000, 26: 307-312. PMID: 10839351, DOI: 10.1016/s0896-6273(00)81165-4.Peer-Reviewed Original ResearchConceptsStiff-man syndromeGlutamic acid decarboxylaseCentral nervous systemInhibitory synapsesEnzyme glutamic acid decarboxylaseHigh-titer autoantibodiesSubset of casesParaneoplastic originClinical featuresSynaptic antigensMediastinal cancerNeurological conditionsRare diseaseGlycine receptorsNervous systemAcid decarboxylaseAutoimmunityPostsynaptic membraneGephyrinSpasmSyndromeSynapsesAutoantibodiesPatientsGABA