2005
Down-regulation of delta-opioid receptors in Na+/H+ exchanger 1 null mutant mouse brain with epilepsy
Zhao P, Ma M, Qian H, Xia Y. Down-regulation of delta-opioid receptors in Na+/H+ exchanger 1 null mutant mouse brain with epilepsy. Neuroscience Research 2005, 53: 442-446. PMID: 16297477, DOI: 10.1016/j.neures.2005.09.003.Peer-Reviewed Original ResearchConceptsDelta-opioid receptorsDOR expressionHippocampal regionGenesis of epilepsyMutant mouse brainNHE1-null miceHippocampal CA1CA3 regionEpilepsy phenotypeEpileptic activityTemporal cortexMouse brainNull miceAutoradiographic resultsUnderlying mechanismEpilepsyImmunohistochemistryCortexMiceBrainReceptorsExpressionNull mutationHippocampusNew cluesIntermittent hypoxia modulates Na+ channel expression in developing mouse brain
Zhao P, Xue J, Gu X, Haddad G, Xia Y. Intermittent hypoxia modulates Na+ channel expression in developing mouse brain. International Journal Of Developmental Neuroscience 2005, 23: 327-333. PMID: 15927756, DOI: 10.1016/j.ijdevneu.2004.12.011.Peer-Reviewed Original Research
2003
Na+ Channel Expression and Neuronal Function in the Na+/H+ Exchanger 1 Null Mutant Mouse
Xia Y, Zhao P, Xue J, Gu X, Sun X, Yao H, Haddad G. Na+ Channel Expression and Neuronal Function in the Na+/H+ Exchanger 1 Null Mutant Mouse. Journal Of Neurophysiology 2003, 89: 229-236. PMID: 12522174, DOI: 10.1152/jn.00488.2002.Peer-Reviewed Original ResearchConceptsChannel expressionMutant miceCA1 neuronsMembrane excitabilityHippocampal CA1 neuronsNull mutant miceRecurrent seizuresCortical neuronsPrevious electrophysiological workNeuronal excitabilityEpileptic seizuresChannel upregulationNeuronal functionCortical regionsCortex formExcitabilityMiceSeizuresHippocampusSubtype IIAltered expressionNeuronsElectrophysiological workImmunoblotting techniquesSubtype I