Congenital nevi versus metastatic melanoma in a newborn to a mother with malignant melanoma – diagnosis supported by sex chromosome analysis and Imaging Mass Spectrometry
Alomari AK, Glusac EJ, Choi J, Hui P, Seeley EH, Caprioli RM, Watsky KL, Urban J, Lazova R. Congenital nevi versus metastatic melanoma in a newborn to a mother with malignant melanoma – diagnosis supported by sex chromosome analysis and Imaging Mass Spectrometry. Journal Of Cutaneous Pathology 2015, 42: 757-764. PMID: 25989266, DOI: 10.1111/cup.12523.Peer-Reviewed Original ResearchConceptsMalignant melanomaCongenital neviInduction of laborLeft upper armThick malignant melanomaChallenging clinical scenarioMultiple mitotic figuresPatient underwentIntravascular invasionSentinel lymphMetastatic lesionsPregnant womenSex chromosome analysisMetastatic melanomaPolymerase chain reactionReddish noduleHistologic examinationResidual melanomaTransplacental metastasisMultiplex polymerase chain reactionDermal proliferationClinical scenariosLesionsNewborn boyUpper arm