1998
Orchestration of neuronal migration by activity of ion channels, neurotransmitter receptors, and intracellular Ca2+ fluctuations
Komuro H, Rakic P. Orchestration of neuronal migration by activity of ion channels, neurotransmitter receptors, and intracellular Ca2+ fluctuations. Developmental Neurobiology 1998, 37: 110-130. PMID: 9777736, DOI: 10.1002/(sici)1097-4695(199810)37:1<110::aid-neu9>3.0.co;2-c.Peer-Reviewed Original ResearchConceptsGranule cellsNeurotransmitter receptorsGranule cell movementN-methyl-D-aspartate (NMDA) subtypeN-type Ca2Different cortical layersIon channelsAcute cerebellar slicesFrequency of Ca2Local cellular milieuPhase of Ca2Position-specific changesVoltage-gated ion channelsGlutamate receptorsSpecific ion channelsCerebellar slicesIntracellular Ca2Transient Ca2Cortical layersReceptor activityNeuronal migrationReceptorsPlasmalemmal surfaceLocal environmental cuesCell migration
1995
Neurotransmitter receptors in the proliferative zones of the developing primate occipital lobe
Lidow M, Rakic P. Neurotransmitter receptors in the proliferative zones of the developing primate occipital lobe. The Journal Of Comparative Neurology 1995, 360: 393-402. PMID: 8543647, DOI: 10.1002/cne.903600303.Peer-Reviewed Original ResearchConceptsCortical neuronsOccipital lobeReceptor subtypesSubventricular zoneHigh-affinity kainate receptorsProliferative zoneSubventricular proliferative zonesNeurotransmitter receptor subtypesCell proliferationEmbryonic cerebral wallGamma-aminobutyric acidD1 dopaminergicMonkey fetusesDeep laminaeKainate receptorsNeuronal productionCerebral wallMultiple neurotransmittersCortical neurogenesisNeurotransmitter receptorsVisual cortexFetusesNeuronsAlpha 1Alpha 2Distribution and density of monoamine receptors in the primate visual cortex devoid of retinal input from early embryonic stages
Rakic P, Lidow. Distribution and density of monoamine receptors in the primate visual cortex devoid of retinal input from early embryonic stages. Journal Of Neuroscience 1995, 15: 2561-2574. PMID: 7891189, PMCID: PMC6578103, DOI: 10.1523/jneurosci.15-03-02561.1995.Peer-Reviewed Original ResearchConceptsMonoamine receptorsVisual cortexLaminar distributionSpecific laminar patternMonths of agePrimate visual cortexGroups of animalsBinocular enucleationCortical consequencesPrestriate areasCerebral cortexMonoaminergic receptorsSupragranular layersCortical plateLayer IVCongenital anophthalmiaGeniculocortical fibersOccipital lobeCortical bindingLaminar patternRetinal inputNeurotransmitter receptorsMonkey striateCoronal planeDistinct laminar
1991
Synchronized overproduction of neurotransmitter receptors in diverse regions of the primate cerebral cortex.
Lidow M, Goldman-Rakic P, Rakic P. Synchronized overproduction of neurotransmitter receptors in diverse regions of the primate cerebral cortex. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 10218-10221. PMID: 1658799, PMCID: PMC52899, DOI: 10.1073/pnas.88.22.10218.Peer-Reviewed Original ResearchSynaptogenesis in Monkey Somatosensory Cortex
Zecevic N, Rakic P. Synaptogenesis in Monkey Somatosensory Cortex. Cerebral Cortex 1991, 1: 510-523. PMID: 1822755, DOI: 10.1093/cercor/1.6.510.Peer-Reviewed Original ResearchConceptsYears of ageSomatosensory cortexSynaptic densityPostcentral gyrusLate fetal ageUpper limb representationDensity of synapsesMonkey somatosensory cortexNumber of synapsesSecond postnatal monthRate of synaptogenesisMicrons 3Timing of synaptogenesisPost-natal lifeSymmetrical synapsesDendritic shaftsSynaptic eliminationSomatosensory functionPostnatal monthDendritic spinesNeocortical areasCortical growthEarly infancyNeurotransmitter receptorsLimb representation
1989
Distribution of major neurotransmitter receptors in the motor and somatosensory cortex of the rhesus monkey
Lidow M, Goldman-Rakic P, Gallager D, Geschwind D, Rakic P. Distribution of major neurotransmitter receptors in the motor and somatosensory cortex of the rhesus monkey. Neuroscience 1989, 32: 609-627. PMID: 2557559, DOI: 10.1016/0306-4522(89)90283-2.Peer-Reviewed Original ResearchConceptsMotor cortexSomatosensory cortexRhesus monkeysNeurotransmitter receptorsMajor neurotransmitter receptorsQuantitative autoradiographic techniqueAdult rhesus monkeysReceptor autoradiographyLaminar distributionReceptor subtypesMotor areaBenzodiazepine receptorsLayer IIIClassical histological techniquesLayer ID2 dopaminergicCortexAutoradiographic techniquesBeta 1Same receptorAlpha 1Alpha 2Different receptorsReceptorsCoextensive distribution
1988
Quantitative autoradiography of major neurotransmitter receptors in the monkey striate and extrastriate cortex
Rakic P, Goldman-Rakic P, Gallager D. Quantitative autoradiography of major neurotransmitter receptors in the monkey striate and extrastriate cortex. Journal Of Neuroscience 1988, 8: 3670-3690. PMID: 2848104, PMCID: PMC6569589, DOI: 10.1523/jneurosci.08-10-03670.1988.Peer-Reviewed Original ResearchConceptsMajor neurotransmitter receptorsArea 17Neurotransmitter receptorsBmax valuesQuinuclidinyl benzilateCortical layersVisual cortical areasAdult rhesus monkeysExtrinsic afferentsCholinergic receptorsCell-packing densityQuantitative autoradiographyCortical areasLaminar patternSpecific laminaeMonkey striateAdult monkeysArea 18Cytoarchitectonic areasEndogenous neurotransmittersLayer IRhesus monkeysBenzilateAlpha 2Receptors