2002
Notch Signaling in the Brain: More than Just a Developmental Story
Šestan N, Rakic P. Notch Signaling in the Brain: More than Just a Developmental Story. Research And Perspectives In Alzheimer's Disease 2002, 19-40. DOI: 10.1007/978-3-642-55996-9_2.Peer-Reviewed Original ResearchNotch signalingNeural developmentCell-cell interaction mechanismCell fate acquisitionCell fate decisionsEarly neural developmentDifferent signaling mechanismsVariety of speciesFate acquisitionNotch signalsCellular phenotypesNotch pathwayMolecular mechanismsSignaling mechanismApoptotic cuesNeuronal differentiationMolecular processesNervous systemAlzheimer's diseaseAdult-onset neurological disordersNeural cellsImportant playersSignalingNeurodegenerative disordersLife span
2000
Programmed Cell Death in Mouse Brain Development
Kuan C, Flavell R, Rakic P. Programmed Cell Death in Mouse Brain Development. Results And Problems In Cell Differentiation 2000, 30: 145-162. PMID: 10857188, DOI: 10.1007/978-3-540-48002-0_6.Peer-Reviewed Original ResearchConceptsCell death machineryMouse brain developmentCell deathDeath machineryNematode Caenorhabditis elegansBasic cellular eventsIdeal experimental systemVertebrate nervous systemBrain developmentCaenorhabditis elegansNormal human brain developmentNerve growth factorGenetic pathwaysTrophic theoryRecent geneSpecific genesCellular eventsGenetic studiesNeural developmentHuman brain developmentTargeted disruptionHigher primatesMechanistic understandingEssential roleGenes