2024
Deviation From Personalized Blood Pressure Targets Correlates With Worse Outcome After Successful Recanalization
Zhang Z, Pu Y, Yu L, Bai H, Duan W, Liu X, Nie X, Wen Z, Zheng L, Hu X, Leng X, Pan Y, Petersen N, Liu L. Deviation From Personalized Blood Pressure Targets Correlates With Worse Outcome After Successful Recanalization. Journal Of The American Heart Association 2024, 13: e033633. PMID: 38533955, PMCID: PMC11179781, DOI: 10.1161/jaha.123.033633.Peer-Reviewed Original ResearchConceptsBlood pressure targetsBlood pressureAutoregulatory limitsWorse outcomesAssociated with symptomatic intracranial hemorrhageAssociated with unfavorable clinical outcomesPressure targetsAssociated with worse outcomesAssociated with poor outcomesSignificant infarction growthSymptomatic intracranial hemorrhageUnfavorable clinical outcomeLarge vessel occlusion strokeAcute ischemic strokeMean velocity indexIntracranial hemorrhageBP management strategiesNeurological deteriorationClinical outcomesInfarct growthPoor outcomeEndovascular thrombectomyOcclusion strokeRecanalizationIschemic stroke
2022
Temporal profiles of systolic blood pressure variability and neurologic outcomes after endovascular thrombectomy
Prasad A, Kobsa J, Kodali S, Bartolome D, Begunova L, Quispe-Orozco D, Farooqui M, Zevallos C, Ortega-Gutiérrez S, Anadani M, Almallouhi E, Spiotta A, Giles J, Keyrouz S, Kim J, Maier I, Liman J, Psychogios M, Riou-Comte N, Richard S, Gory B, Wolfe S, Brown P, Fargen K, Mistry E, Fakhri H, Mistry A, Wong K, Nascimento F, Kan P, de Havenon A, Sheth K, Petersen N. Temporal profiles of systolic blood pressure variability and neurologic outcomes after endovascular thrombectomy. European Stroke Journal 2022, 7: 365-375. PMID: 36478756, PMCID: PMC9720854, DOI: 10.1177/23969873221106907.Peer-Reviewed Original ResearchBlood pressure variabilitySystolic blood pressure variabilityHigh systolic blood pressure variabilityEndovascular thrombectomyFunctional outcomePressure variabilityHigh blood pressure variabilityLower blood pressure variabilityAcute ischemic stroke patientsLarge vessel occlusion strokePoor discharge outcomeIschemic stroke patientsWorse functional outcomePoor functional outcomeBlood pressure dataHigh trajectory groupGroup-based trajectory modelingHemorrhagic transformationNeurologic outcomeDischarge outcomesSBP trajectoriesStroke patientsOcclusion strokePoor outcomeRelevant confounders