2008
Antigen‐induced Lymph Node Remodeling: LVs, HEVs and Conduits
Stranford S, Liao S, Bentley K, Ruddle F, Ruddle N. Antigen‐induced Lymph Node Remodeling: LVs, HEVs and Conduits. The FASEB Journal 2008, 22: 392.3-392.3. DOI: 10.1096/fasebj.22.1_supplement.392.3.Peer-Reviewed Original ResearchHigh endothelial venulesLymph nodesAntigen encounterLymphatic vesselsLymph node remodelingLYVE-1T cell areasSecondary lymphoid organsAntigen-specific lymphocytesER-TR7Lymphoid organsAfferent lymphaticsEndothelial venulesMice transgenicTransgenic miceVascular interactionsDay 4Endothelial cellsAbluminal surfaceLymphocytesAntigenMarkersExpressionEGFP expressionVessels
1993
Mice Transgenic for HTLV-I LTR-tax Exhibit Tax Expression in Bone, Skeletal Alterations, and High Bone Turnover
Ruddle N, Li C, Horn W, Santiago P, Troiano N, Jay G, Horowitz M, Baron R. Mice Transgenic for HTLV-I LTR-tax Exhibit Tax Expression in Bone, Skeletal Alterations, and High Bone Turnover. Virology 1993, 197: 196-204. PMID: 8212554, DOI: 10.1006/viro.1993.1580.Peer-Reviewed Original ResearchConceptsHigh bone turnoverHTLV-I infectionBone turnoverMice transgenicSkeletal alterationsAdult T-cell leukemiaMonths of ageSpindle-shaped cellsT-cell leukemiaBone cell activityPaget's diseaseViral etiologyOsteoclast numberBone resorptionPathogenetic mechanismsBone diseaseCell leukemiaBone marrowCell activitySkeletal changesTax mRNASevere skeletal abnormalitiesHost factorsDiseaseSkeletal abnormalities