Simultaneous determination of uric acid metabolites allantoin, 6-aminouracil, and triuret in human urine using liquid chromatography–mass spectrometry
Kim KM, Henderson GN, Frye RF, Galloway CD, Brown NJ, Segal MS, Imaram W, Angerhofer A, Johnson RJ. Simultaneous determination of uric acid metabolites allantoin, 6-aminouracil, and triuret in human urine using liquid chromatography–mass spectrometry. Journal Of Chromatography B 2008, 877: 65-70. PMID: 19081307, PMCID: PMC2684329, DOI: 10.1016/j.jchromb.2008.11.029.Peer-Reviewed Original ResearchMeSH KeywordsAllantoinCalibrationChromatography, High Pressure LiquidHumansReference StandardsReproducibility of ResultsSpectrometry, Mass, Electrospray IonizationUracilUreaConceptsUric acidUrinary metabolitesOxidative stressSelected-reaction monitoringUrinary creatinineNormal individualsNitric oxideUrine samplesLiquid chromatography-mass spectrometryBiological samplesPositive ion modeTandem mass spectrometry methodHigh-performance liquid chromatographyMass spectrometry methodChromatography-mass spectrometryUrineInter-day precisionMetabolitesUrinary allantoinIon modeLC-MS/MS analysisHuman urineGradient HPLCMost mammalsSpectrometry method