2011
Time course of regional brain activity accompanying auditory verbal hallucinations in schizophrenia
Hoffman RE, Pittman B, Constable RT, Bhagwagar Z, Hampson M. Time course of regional brain activity accompanying auditory verbal hallucinations in schizophrenia. The British Journal Of Psychiatry 2011, 198: 277-283. PMID: 21972276, PMCID: PMC3065772, DOI: 10.1192/bjp.bp.110.086835.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainBrain MappingFemaleFrontal LobeHallucinationsHemodynamicsHumansMagnetic Resonance ImagingMaleOxygenSchizophreniaSchizophrenic PsychologyTemporal LobeTime FactorsConceptsInferior frontal gyrusAuditory verbal hallucinationsFrontal gyrusVerbal hallucinationsRegional brain activityTemporal regionsHallucination eventsBrain activityRight inferior frontal gyrusFunctional magnetic resonance imagingRight temporal activityRight posterior temporal regionPosterior temporal regionsEffects of motorNon-hallucinating patientsRight temporal regionHallucinations groupLeft temporal regionMagnetic resonance imagingTime courseCorollary dischargeGyrusVerbal imagesRegional activitySchizoaffective disorder
2010
Elevated Functional Connectivity Along a Corticostriatal Loop and the Mechanism of Auditory/Verbal Hallucinations in Patients with Schizophrenia
Hoffman RE, Fernandez T, Pittman B, Hampson M. Elevated Functional Connectivity Along a Corticostriatal Loop and the Mechanism of Auditory/Verbal Hallucinations in Patients with Schizophrenia. Biological Psychiatry 2010, 69: 407-414. PMID: 21145042, PMCID: PMC3039042, DOI: 10.1016/j.biopsych.2010.09.050.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsAntipsychotic AgentsCerebral CortexDiagnostic and Statistical Manual of Mental DisordersFemaleFrontal LobeHallucinationsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleNeostriatumNeural PathwaysNeuropsychological TestsPutamenSchizophreniaSchizophrenic PsychologySocioeconomic FactorsTemporal LobeVerbal BehaviorConceptsHealthy control subjectsControl subjectsFunctional connectivityNonhallucinating patientsPatient groupInferior frontal gyrusAuditory/verbal hallucinationsCorticostriatal loopsElevated functional connectivityVerbal hallucinationsFalse discovery rate correctionFunctional magnetic resonancePatientsSubcortical regionsLeft inferior frontal gyrusSeed regionPutamenFrontal gyrusSpeech processing networkFunctional coordinationNeural activitySchizophreniaFC relativeHigh levelsHallucinations
2008
Time course of regional brain activation associated with onset of auditory/verbal hallucinations
Hoffman RE, Anderson AW, Varanko M, Gore JC, Hampson M. Time course of regional brain activation associated with onset of auditory/verbal hallucinations. The British Journal Of Psychiatry 2008, 193: 424-425. PMID: 18978327, PMCID: PMC2801815, DOI: 10.1192/bjp.bp.107.040501.Peer-Reviewed Original ResearchMeSH KeywordsAuditory CortexBrainGyrus CinguliHallucinationsHumansParahippocampal GyrusSchizophrenic PsychologyTime FactorsConceptsVerbal hallucinationsBrain activationRight middle temporal gyrusRegional brain activationLeft anterior insulaFunctional magnetic resonanceMiddle temporal gyrusPrevious case reportsAnterior insulaTemporal gyrusBrain eventsAnterior cingulateDextral patientsTime courseParahippocampal gyrusCase reportHallucinationsGyrusActivationMagnetic resonanceOnsetInsulaCingulate