2013
Hoarding disorder and obsessive–compulsive disorder show different patterns of neural activity during response inhibition
Tolin DF, Witt ST, Stevens MC. Hoarding disorder and obsessive–compulsive disorder show different patterns of neural activity during response inhibition. Psychiatry Research 2013, 221: 142-148. PMID: 24389161, PMCID: PMC3946244, DOI: 10.1016/j.pscychresns.2013.11.009.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderGo/NoGo taskFunctional magnetic resonance imagingOCD patientsHD patientsResponse inhibitionNoGo taskHealthy controlsGo/NoGo task performanceDistinct neural underpinningsRight orbitofrontal gyrusErrors of commissionNeural underpinningsOrbitofrontal activationTask performanceCorrect rejectsMagnetic resonance imagingHemodynamic activityFrontal hypoactivityNeural activityOrbitofrontal gyrusBehavioral dataHemodynamic responsePatientsPreliminary evidence
2012
fMRI task parameters influence hemodynamic activity in regions implicated in mental set switching
Witt ST, Stevens MC. fMRI task parameters influence hemodynamic activity in regions implicated in mental set switching. NeuroImage 2012, 65: 139-151. PMID: 23079572, PMCID: PMC3523276, DOI: 10.1016/j.neuroimage.2012.09.072.Peer-Reviewed Original ResearchConceptsBrain regionsMagnetic resonance imaging studySecondary visual cortexResonance imaging studyFunctional magnetic resonance imaging studySensorimotor cortexFronto-parietal regionsAnterior prefrontal cortexAnterior cingulateVisual cortexImaging studiesFronto-parietal networkPrefrontal cortexHemodynamic activityCortexBrain activityComplex executive functionsStimulus complexityExecutive functionResponse complexityTrialsNon-switch trialsPrevious studies
2007
An fMRI Auditory Oddball Study of Combined-Subtype Attention Deficit Hyperactivity Disorder
Stevens MC, Pearlson GD, Kiehl KA. An fMRI Auditory Oddball Study of Combined-Subtype Attention Deficit Hyperactivity Disorder. American Journal Of Psychiatry 2007, 164: 1737-1749. PMID: 17974940, DOI: 10.1176/appi.ajp.2007.06050876.Peer-Reviewed Original ResearchMeSH KeywordsAcoustic StimulationAdolescentAdolescent BehaviorAttentionAttention Deficit Disorder with HyperactivityAuditory PerceptionBrainBrain MappingCerebral CortexChildCognition DisordersDiagnostic and Statistical Manual of Mental DisordersEvoked PotentialsHemodynamicsHumansMagnetic Resonance ImagingMaleMemory DisordersOrientationOxygenPsychiatric Status Rating ScalesPsychomotor PerformanceConceptsAttention deficit hyperactivity disorderEvent-related potentialsFunctional magnetic resonance imagingDeficit hyperactivity disorderBrain regionsHyperactivity disorderHemodynamic activityThree-stimulus auditory oddball taskP3 event-related potentialEvent-related fMRI dataProcessing of targetsAbnormal hemodynamic activityWorking Memory DeficitsSlower task performanceAuditory oddball taskNovel environmental stimuliCortical brain regionsAttentional orientingOrient attentionADHD participantsCognitive processesCognitive representationsOddball studiesNeurobiological theoriesOddball stimuli
2005
fMRI in an oddball task: Effects of target‐to‐target interval
Stevens MC, Calhoun VD, Kiehl KA. fMRI in an oddball task: Effects of target‐to‐target interval. Psychophysiology 2005, 42: 636-642. PMID: 16364059, DOI: 10.1111/j.1469-8986.2005.00368.x.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingEvent-related potentialsTarget stimuliOddball taskTarget intervalTask-relevant target stimuliP3 event-related potentialBilateral lateral prefrontal cortexTask-relevant stimuliTemporal-parietal junctionLateral prefrontal cortexAuditory oddball taskMemory templateNovel stimuliPrefrontal cortexHemodynamic activityAnterior cingulateNeural systemsStimuliPositive relationshipLarge sampleHealthy adultsNeuronal modulationEffect of targetMagnetic resonance imagingThe hemodynamics of oddball processing during single-tone and two-tone target detection tasks
Stevens MC, Laurens KR, Liddle PF, Kiehl KA. The hemodynamics of oddball processing during single-tone and two-tone target detection tasks. International Journal Of Psychophysiology 2005, 60: 292-303. PMID: 16213043, PMCID: PMC2766532, DOI: 10.1016/j.ijpsycho.2005.07.012.Peer-Reviewed Original ResearchConceptsContextual manipulationsStimulus processingOddball taskTwo-tone auditory oddball taskEvent-related potential studySalient stimuli processingTarget stimulus processingBilateral temporal cortexTarget detection taskAuditory oddball taskLateral frontal cortexERP componentsReflexive processingSalient stimuliStimulus typeERP dataTask performanceFMRI studyStimulus classesDetection taskNeurocognitive functionSubcortical networksNeural systemsPotential studiesTemporal cortexLow-dose estradiol alters brain activity
Stevens MC, Clark VP, Prestwood KM. Low-dose estradiol alters brain activity. Psychiatry Research 2005, 139: 199-217. PMID: 16084069, DOI: 10.1016/j.pscychresns.2005.04.004.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingSustained attention taskAttention taskEvent-related functional magnetic resonance imagingThree-stimulus oddball taskTasks of learningAlters brain activityEstrogen replacement therapyCortical brain regionsOddball taskBehavioral performanceBrain activityPrefrontal cortexHemodynamic activityAnterior cingulateDose estrogen replacement therapyNeural activityParietal lobeBrain regionsBrain functionReplacement therapyTaskGroup participantsDouble-blind studyMotor cortexAbnormal hemodynamics in schizophrenia during an auditory oddball task
Kiehl KA, Stevens MC, Celone K, Kurtz M, Krystal JH. Abnormal hemodynamics in schizophrenia during an auditory oddball task. Biological Psychiatry 2005, 57: 1029-1040. PMID: 15860344, PMCID: PMC2771438, DOI: 10.1016/j.biopsych.2005.01.035.Peer-Reviewed Original ResearchConceptsAuditory oddball taskHealthy participantsOddball taskThree-stimulus auditory oddball taskDiffuse brain abnormalitiesHealthy control subjectsNovelty processingWidespread pathologic processCerebral areasControl subjectsBrain abnormalitiesMagnetic resonance imaging dataAbnormal hemodynamicsPathologic processesSchizophrenia patientsParietal cortexCognitive functionHeterogeneous disorderCerebellar circuitsSchizophreniaAbnormalitiesSignificant activationSubcortical systemsFunctional magnetic resonance imaging (fMRI) dataPatientsAn adaptive reflexive processing model of neurocognitive function: supporting evidence from a large scale (n = 100) fMRI study of an auditory oddball task
Kiehl KA, Stevens MC, Laurens KR, Pearlson G, Calhoun VD, Liddle PF. An adaptive reflexive processing model of neurocognitive function: supporting evidence from a large scale (n = 100) fMRI study of an auditory oddball task. NeuroImage 2005, 25: 899-915. PMID: 15808990, DOI: 10.1016/j.neuroimage.2004.12.035.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsArousalAttentionBrainBrain MappingDominance, CerebralEvent-Related Potentials, P300FemaleHemodynamicsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNerve NetOxygenPitch DiscriminationReaction TimeReflexSex FactorsStatistics as TopicConceptsTask performanceNovel stimuliTask-relevant target stimuliProcessing of salientBrain regionsSuccessful task performanceAuditory oddball taskFunctional MRI studyNovelty processingReflexive processingSalient stimuliTarget stimuliOddball taskFMRI studyRandom effects statistical modelSubcortical systemsProcessing modelEffect of genderNeurocognitive functionInter-subject reliabilityEffects statistical modelStimuliSignificant activationFixed-effects analysisTarget detection
2004
fMRI analysis with the general linear model: removal of latency-induced amplitude bias by incorporation of hemodynamic derivative terms
Calhoun VD, Stevens MC, Pearlson GD, Kiehl KA. fMRI analysis with the general linear model: removal of latency-induced amplitude bias by incorporation of hemodynamic derivative terms. NeuroImage 2004, 22: 252-257. PMID: 15110015, DOI: 10.1016/j.neuroimage.2003.12.029.Peer-Reviewed Original Research