2024
Confinement induces internal flows in adherent cell aggregates
Yousafzai M, Amiri S, Sun Z, Pahlavan , Murrell M. Confinement induces internal flows in adherent cell aggregates. Journal Of The Royal Society Interface 2024, 21: 20240105. PMID: 38774959, PMCID: PMC11285874, DOI: 10.1098/rsif.2024.0105.Peer-Reviewed Original Research
2022
Interplay between substrate rigidity and tissue fluidity regulates cell monolayer spreading
Staddon M, Murrell M, Banerjee S. Interplay between substrate rigidity and tissue fluidity regulates cell monolayer spreading. Soft Matter 2022, 18: 7877-7886. PMID: 36205535, PMCID: PMC9700261, DOI: 10.1039/d2sm00757f.Peer-Reviewed Original ResearchConceptsSubstrate rigidityCollective cell motionSubstrate stiffnessTissue fluidityStiff substratesCell-matrix adhesionTraction force generationCell-cell interactionsCell motionTissue morphogenesisSoft elastic matrixCell collectivesEmbryonic developmentCell crawlingCell spreadingCell monolayersSolid tissuesCell behaviorMechanical behaviorPredictive understandingMechanical propertiesCancer invasionCell aggregatesElastic matrixCell properties
2014
How cells flow in the spreading of cellular aggregates
Beaune G, Stirbat T, Khalifat N, Cochet-Escartin O, Garcia S, Gurchenkov V, Murrell M, Dufour S, Cuvelier D, Brochard-Wyart F. How cells flow in the spreading of cellular aggregates. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 8055-8060. PMID: 24835175, PMCID: PMC4050549, DOI: 10.1073/pnas.1323788111.Peer-Reviewed Original Research
2012
F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex
Murrell M, Gardel M. F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 20820-20825. PMID: 23213249, PMCID: PMC3529094, DOI: 10.1073/pnas.1214753109.Peer-Reviewed Original Research