2024
Mechanical power is maximized during contractile ring-like formation in a biomimetic dividing cell model
Sakamoto R, Murrell M. Mechanical power is maximized during contractile ring-like formation in a biomimetic dividing cell model. Nature Communications 2024, 15: 9731. PMID: 39523366, PMCID: PMC11551154, DOI: 10.1038/s41467-024-53228-y.Peer-Reviewed Original ResearchMeSH KeywordsActin CytoskeletonActinsActomyosinAnimalsBiomechanical PhenomenaBiomimeticsCell DivisionModels, BiologicalMyosinsUnilamellar LiposomesConceptsMyosin-induced stressContractile ring assemblyCell division mechanismActin filamentsActin cortexCleavage furrowDivision planeActomyosin flowsGiant unilamellar vesiclesRing assemblyCell divisionMyosin activityContractile ring-like structureShape changesRing-like structureDivision mechanismEnergetic costSymmetric divisionActinRing-like formationCell modelUnilamellar vesiclesIn vitro modelFurrowCellsF-actin architecture determines the conversion of chemical energy into mechanical work
Sakamoto R, Murrell M. F-actin architecture determines the conversion of chemical energy into mechanical work. Nature Communications 2024, 15: 3444. PMID: 38658549, PMCID: PMC11043346, DOI: 10.1038/s41467-024-47593-x.Peer-Reviewed Original ResearchMeSH KeywordsActin CytoskeletonActinsAdenosine TriphosphateAnimalsBiomechanical PhenomenaHydrolysisMyosin Type IIMyosinsRabbitsConceptsF-actin architectureF-actinATP consumption rateF-actin bundlesIn vitro reconstitutionDynamic cellular processesHigher ATP consumptionActin cytoskeletonFilamentous actinMyosin motorsCellular processesATP hydrolysisPurified componentsAdenosine triphosphateForce generationConversion of chemical energyATP consumptionConsumption rateActinChemical energyMyosinNetwork contractionCytoskeletonEnergetic principlesHydrolysis
2011
Spreading Dynamics of Biomimetic Actin Cortices
Murrell M, Pontani L, Guevorkian K, Cuvelier D, Nassoy P, Sykes C. Spreading Dynamics of Biomimetic Actin Cortices. Biophysical Journal 2011, 100: 1400-1409. PMID: 21402021, PMCID: PMC3059579, DOI: 10.1016/j.bpj.2011.01.038.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsBiomechanical PhenomenaBiomimetic MaterialsCell MembraneHydrodynamicsLiposomesModels, Biological