2023
Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex
Sakamoto R, Banerjee D, Yadav V, Chen S, Gardel M, Sykes C, Banerjee S, Murrell M. Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex. Communications Biology 2023, 6: 325. PMID: 36973388, PMCID: PMC10043271, DOI: 10.1038/s42003-023-04684-7.Peer-Reviewed Original ResearchConceptsF-actin reorganizationMechanical stressCell cortexBiochemical regulationCell shapeActomyosin cortexPhysical behaviorCell polarizationMembrane tensionCell migrationEssential physical behaviorPore openingSpatial assemblyDrive changesMembraneRelative rolesStressActinRegulationDiverse behaviorsRoleAssembly
2022
Gradients in solid surface tension drive Marangoni-like motions in cell aggregates
Yadav V, Yousafzai S, Amiri S, Style R, Dufresne E, Murrell M. Gradients in solid surface tension drive Marangoni-like motions in cell aggregates. Physical Review Fluids 2022, 7: l031101. DOI: 10.1103/physrevfluids.7.l031101.Peer-Reviewed Original ResearchSurface tension gradientTension gradientSurface tensionElastic deformationActive stressSurface strainSurface stressViscous fluidViscoelastic relaxationMechanical strainReverse motionToroidal motionMotionLaser ablationMarangoniGradientSimple tissueStressDeformationTissue shapeTensionAggregatesSurfaceOriginal position
2014
Liposome adhesion generates traction stress
Murrell M, Voituriez R, Joanny J, Nassoy P, Sykes C, Gardel M. Liposome adhesion generates traction stress. Nature Physics 2014, 10: 163-169. DOI: 10.1038/nphys2855.Peer-Reviewed Original ResearchMembrane tensionLarger traction stressCellular force generationTraction stressEssential life processesRole of membraneCellular length scalesCell tensionLife processesGlobal shape changesMechanical forcesMembraneShape changesForce generationAdhesionCytoskeletonLiposome adhesionStressRoleMechanical stressCellsCompliant substratesDivision