2024
Active tension and membrane friction mediate cortical flows and blebbing in a model actomyosin cortex
Sakamoto R, Murrell M. Active tension and membrane friction mediate cortical flows and blebbing in a model actomyosin cortex. Physical Review Research 2024, 6: 033024. DOI: 10.1103/physrevresearch.6.033024.Peer-Reviewed Original ResearchActomyosin cortexCell membraneActin cytoskeletonCortical flowMembrane blebbingCell divisionCell migrationCytoskeletonActomyosinBiological phenomenaMembrane bulgesBlebsCellsMembraneViscoelastic fluidMechanical responseElastic stressesStress yieldActinUbiquitous structuresApoptosisMechanical stressMembrane elasticityPhysical behavior
2023
Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex
Sakamoto R, Banerjee D, Yadav V, Chen S, Gardel M, Sykes C, Banerjee S, Murrell M. Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex. Communications Biology 2023, 6: 325. PMID: 36973388, PMCID: PMC10043271, DOI: 10.1038/s42003-023-04684-7.Peer-Reviewed Original ResearchConceptsF-actin reorganizationMechanical stressCell cortexBiochemical regulationCell shapeActomyosin cortexPhysical behaviorCell polarizationMembrane tensionCell migrationEssential physical behaviorPore openingSpatial assemblyDrive changesMembraneRelative rolesStressActinRegulationDiverse behaviorsRoleAssembly
2014
Liposome adhesion generates traction stress
Murrell M, Voituriez R, Joanny J, Nassoy P, Sykes C, Gardel M. Liposome adhesion generates traction stress. Nature Physics 2014, 10: 163-169. DOI: 10.1038/nphys2855.Peer-Reviewed Original ResearchMembrane tensionLarger traction stressCellular force generationTraction stressEssential life processesRole of membraneCellular length scalesCell tensionLife processesGlobal shape changesMechanical forcesMembraneShape changesForce generationAdhesionCytoskeletonLiposome adhesionStressRoleMechanical stressCellsCompliant substratesDivision