2007
Development of Cortical Maps: Perspectives From the Barrel Cortex
Inan M, Crair MC. Development of Cortical Maps: Perspectives From the Barrel Cortex. The Neuroscientist 2007, 13: 49-61. PMID: 17229975, DOI: 10.1177/1073858406296257.Peer-Reviewed Original ResearchConceptsBarrel mapThalamic axonsBarrel cortexBarrel map formationActivity-dependent cuesMolecular cuesSensory afferentsMotor cortexPrimary somatosensoryThalamocortical axonsSomatosensory cortexCortical neuronsSynapse maturationNeuronal activityFunctional maturationVentricular cellsCortical mapsCortexAxonsNeocortical developmentWiring principlesCortical patterningMammalian neocortexNeocortexNeurons
1999
The Nuclear Orphan Receptor COUP-TFI Is Required for Differentiation of Subplate Neurons and Guidance of Thalamocortical Axons
Zhou C, Qiu Y, Pereira F, Crair M, Tsai S, Tsai M. The Nuclear Orphan Receptor COUP-TFI Is Required for Differentiation of Subplate Neurons and Guidance of Thalamocortical Axons. Neuron 1999, 24: 847-859. PMID: 10624948, DOI: 10.1016/s0896-6273(00)81032-6.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntimetabolitesAxonsBromodeoxyuridineCarbocyaninesCell DeathCell DifferentiationCerebral CortexCOUP Transcription Factor IDNA-Binding ProteinsFluorescent DyesImmunohistochemistryIn Situ HybridizationMaleMiceMutationNeural PathwaysNeuronsReceptors, GlucocorticoidThalamusTranscription FactorsConceptsSubplate neuronsThalamocortical projectionsCortical layer IVLayer IV neuronsCell deathCorticothalamic connectivityAfferent innervationCerebral cortexThalamocortical axonsLayer IVNervous systemExcessive cell deathFactor INeuronal developmentNeuronsNuclear receptorsPremature cell deathInnervationImproper differentiationImportant regulatorOrphan memberDeathCritical roleDifferentiationFailureAltered spatial patterns of functional thalamocortical connections in the barrel cortex after neonatal infraorbital nerve cut revealed by optical recording
Higashi S, Crair MC, Kurotani T, Inokawa H, Toyama K. Altered spatial patterns of functional thalamocortical connections in the barrel cortex after neonatal infraorbital nerve cut revealed by optical recording. Neuroscience 1999, 91: 439-452. PMID: 10366001, DOI: 10.1016/s0306-4522(98)00666-6.Peer-Reviewed Original ResearchConceptsInfraorbital nerve cutNerve cutNormal ratsLayer IVSomatosensory cortexDextran amine labelingThalamocortical slice preparationPostnatal day 7Cytochrome oxidase stainingThalamocortical transmissionThalamocortical connectionsDextran amineThalamocortical axonsThalamic stimulationBarrel cortexFunctional synapsesSlice preparationAxon terminalsVoltage-sensitive dyeTerminal arborsAltered spatial patternDay 7P5-P6RatsBarrel formation