2001
Barrel Cortex Critical Period Plasticity Is Independent of Changes in NMDA Receptor Subunit Composition
Lu H, Gonzalez E, Crair M. Barrel Cortex Critical Period Plasticity Is Independent of Changes in NMDA Receptor Subunit Composition. Neuron 2001, 32: 619-634. PMID: 11719203, DOI: 10.1016/s0896-6273(01)00501-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain MappingCritical Period, PsychologicalExcitatory Amino Acid AntagonistsExcitatory Postsynaptic PotentialsGene Expression Regulation, DevelopmentalLong-Term PotentiationMiceMice, Inbred C57BLMice, KnockoutNeuronal PlasticityPiperidinesQuinoxalinesReceptors, AMPAReceptors, N-Methyl-D-AspartateSomatosensory CortexSynapsesThalamusConceptsNMDA receptor subunit compositionReceptor subunit compositionSubunit compositionMouse somatosensory barrel cortexCritical periodNR2A knockout miceCritical period plasticitySomatosensory barrel cortexNMDAR subunit compositionCurrent kineticsAfferent innervationBarrel cortexNR2B subunitKnockout miceSynaptic plasticityNR2A subunitPlasticity windowSubunits
1999
The Nuclear Orphan Receptor COUP-TFI Is Required for Differentiation of Subplate Neurons and Guidance of Thalamocortical Axons
Zhou C, Qiu Y, Pereira F, Crair M, Tsai S, Tsai M. The Nuclear Orphan Receptor COUP-TFI Is Required for Differentiation of Subplate Neurons and Guidance of Thalamocortical Axons. Neuron 1999, 24: 847-859. PMID: 10624948, DOI: 10.1016/s0896-6273(00)81032-6.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntimetabolitesAxonsBromodeoxyuridineCarbocyaninesCell DeathCell DifferentiationCerebral CortexCOUP Transcription Factor IDNA-Binding ProteinsFluorescent DyesImmunohistochemistryIn Situ HybridizationMaleMiceMutationNeural PathwaysNeuronsReceptors, GlucocorticoidThalamusTranscription FactorsConceptsSubplate neuronsThalamocortical projectionsCortical layer IVLayer IV neuronsCell deathCorticothalamic connectivityAfferent innervationCerebral cortexThalamocortical axonsLayer IVNervous systemExcessive cell deathFactor INeuronal developmentNeuronsNuclear receptorsPremature cell deathInnervationImproper differentiationImportant regulatorOrphan memberDeathCritical roleDifferentiationFailure