2001
Methylprednisolone and Acute Spinal Cord Injury
Bracken M. Methylprednisolone and Acute Spinal Cord Injury. Spine 2001, 26: s47-s54. PMID: 11805609, DOI: 10.1097/00007632-200112151-00010.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryCord injuryMethodologic qualitySystematic reviewImproved functional recoveryHigh methodologic qualityNeurologic recoveryClinical recoveryPharmacologic therapyFunctional recoveryRandomized trialsInjury trialsCochrane LibraryEffective therapySurgical trialsEarly treatmentFurther trialsTherapeutic interventionsInjuryMeSH headingsMethylprednisoloneScore improvementPatientsEvidence base
1998
Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up. Results of the third National Acute Spinal Cord Injury randomized controlled trial.
Bracken M, Shepard M, Holford T, Leo-Summers L, Aldrich E, Fazl M, Fehlings M, Herr D, Hitchon P, Marshall L, Nockels R, Pascale V, Perot P, Piepmeier J, Sonntag V, Wagner F, Wilberger J, Winn H, Young W. Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up. Results of the third National Acute Spinal Cord Injury randomized controlled trial. Journal Of Neurosurgery 1998, 89: 699-706. PMID: 9817404, DOI: 10.3171/jns.1998.89.5.0699.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryHours of injuryCord injuryFunctional recoveryRandomized double-blind clinical trialMortality rate 1 yearDouble-blind clinical trialMotor function recoveryMP regimenMotor recoveryMP therapyTherapy 3Neurological gradeMorbidity rateSphincter controlFunction recoveryMethylprednisolone regimenClinical trialsMedical factorsTreatment groupsPatientsRegimenInjurySelf-CareMethylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up
Bracken M, Shepard M, Holford T, Leo-Summers L, Aldrich E, Fazl M, Fehlings M, Herr D, Hitchon P, Marshall L, Nockels R, Pascale V, Perot P, Piepmeier J, Sonntag V, Wagner F, Wilberger J, Winn H, Young W. Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up. Neurosurgical FOCUS 1998, 5: e1. DOI: 10.3171/foc.1998.5.3.1.Peer-Reviewed Original ResearchAcute spinal cord injuryHours of injurySpinal cord injuryFunctional recoveryCord injuryMortality rate 1 yearDouble-blind clinical trialMotor function recoveryMP regimenMethods PatientsMotor recoveryMP therapyTherapy 3Neurological gradeMorbidity rateSphincter controlFunction recoveryMethylprednisolone regimenClinical trialsMedical factorsTreatment groupsPatientsRegimenInjurySelf-Care
1992
The Second National Acute Spinal Cord Injury Study.
Young W, Bracken M. The Second National Acute Spinal Cord Injury Study. Journal Of Neurotrauma 1992, 9 Suppl 1: s397-405. PMID: 1588630.Peer-Reviewed Original ResearchConceptsSecond National Acute Spinal Cord Injury StudyNational Acute Spinal Cord Injury StudyAcute Spinal Cord Injury StudySpinal Cord Injury StudySpinal cord injuryNeurologic scoresCord injuryInjury studiesHuman spinal cord injurySpinal cord injury careSevere spinal cord injuryBeneficial effectsSignificant beneficial effectNeurologic recoverySuch patientsPatient populationInjury careLumbosacral segmentsFunctional assessmentLesion siteInjury severityPatientsSensory functionMultivariate analysisMethylprednisoloneMethylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. Results of the second National Acute Spinal Cord Injury Study.
Bracken M, Shepard M, Collins W, Holford T, Baskin D, Eisenberg H, Flamm E, Leo-Summers L, Maroon J, Marshall L, Perot P, Piepmeier J, Sonntag V, Wagner F, Wilberger J, Winn H, Young W. Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. Results of the second National Acute Spinal Cord Injury Study. Journal Of Neurosurgery 1992, 76: 23-31. PMID: 1727165, DOI: 10.3171/jns.1992.76.1.0023.Peer-Reviewed Original ResearchConceptsHours of injuryAcute spinal cord injurySpinal cord injuryNaloxone treatmentCord injuryMotor functionSecond National Acute Spinal Cord Injury StudyNational Acute Spinal Cord Injury StudyAcute Spinal Cord Injury StudySpinal Cord Injury StudyAcute spinal cord traumaPreservation of motorTrial of methylprednisoloneSpinal cord traumaTotal sensoryPlacebo groupCord traumaNeurological functionStudy doseEmergency roomMethylprednisoloneInjury studiesMortality ratePatientsSensory function
1991
Premature rupture of membranes at preterm. Meta-analysis of the effect of steroids on the prevention of respiratory distress syndrome.
Oyarzún E, Gómez R, Romero R, Bracken M. Premature rupture of membranes at preterm. Meta-analysis of the effect of steroids on the prevention of respiratory distress syndrome. Revista Medica De Chile 1991, 119: 388-95. PMID: 1842981.Peer-Reviewed Original ResearchConceptsRespiratory distress syndromeFetal respiratory distress syndromeUse of steroidsPremature ruptureDistress syndromeEffects of steroidsInfectious complicationsSteroid treatmentPregnant womenRelative riskSteroidsSyndromeConfidence intervalsComplicationsRupturePretermNeonatesPatientsPreventionWomen
1990
A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury
Bracken M, Shepard M, Collins W, Holford T, Young W, Baskin D, Eisenberg H, Flamm E, Leo-Summers L, Maroon J, Marshall L, Perot P, Piepmeier J, Sonntag V, Wagner F, Wilberger J, Winn H. A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury. New England Journal Of Medicine 1990, 322: 1405-1411. PMID: 2278545, DOI: 10.1056/nejm199005173222001.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryNeurologic recoverySafety of methylprednisoloneSystematic neurological examinationPlacebo-controlled trialHours of injuryMajor morbidityNeurologic outcomeControlled TrialsNeurological examinationIncomplete lesionsMotor functionMethylprednisoloneNaloxonePatientsBody weightSensory functionInjuryPlaceboInfusionBolusEffective remainsTreatmentDose
1987
THE ASSOCIATION BETWEEN LOW BIRTH WEIGHT AND CAFFEINE CONSUMPTION DURING PREGNANCY
MARTIN T, BRACKEN M. THE ASSOCIATION BETWEEN LOW BIRTH WEIGHT AND CAFFEINE CONSUMPTION DURING PREGNANCY. American Journal Of Epidemiology 1987, 126: 813-821. PMID: 3661529, DOI: 10.1093/oxfordjournals.aje.a114718.Peer-Reviewed Original ResearchConceptsLow birth weightBirth weightGestational ageCaffeine intakeCaffeine consumptionYale-New Haven HospitalMaternal caffeine intakeMean birth weightWeeks gestational ageAntenatal patientsSingleton newbornsTerm newbornsProspective studyCaffeine dailyRelative riskCaffeine exposureGrowth retardationDose responseNewbornsIntakeAgeRiskPregnancyPatientsHospital
1985
Sonographically monitored amniocentesis to decrease intraoperative complications.
Romero R, Jeanty P, Reece E, Grannum P, Bracken M, Berkowitz R, Hobbins J. Sonographically monitored amniocentesis to decrease intraoperative complications. Obstetrics And Gynecology 1985, 65: 426-30. PMID: 3883268.Peer-Reviewed Original Research
1981
Psychological response to acute spinal cord injury: an epidemiological study
Bracken M, Shepard M, Webb S. Psychological response to acute spinal cord injury: an epidemiological study. Spinal Cord 1981, 19: 271-283. PMID: 7279429, DOI: 10.1038/sc.1981.53.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCord injuryAcute spinal cord injurySeverity of motorTime of dischargeAcute care hospitalsAcute hospitalisationNeurological statusCare hospitalNeurological functionPsychological reactionsEpidemiological studiesRehabilitation therapyInjuryNegative coping responsesHospitalisationPsychological counsellingSensory disabilitiesPersonality reactionsPsychological responsesLesser degreeCoping reactionsPatientsAdmissionHospitalINCIDENCE OF ACUTE TRAUMATIC HOSPITALIZED SPINAL CORD INJURY IN THE UNITED STATES, 1970–19771
BRACKEN M, FREEMAN D, HELLENBRAND K. INCIDENCE OF ACUTE TRAUMATIC HOSPITALIZED SPINAL CORD INJURY IN THE UNITED STATES, 1970–19771. American Journal Of Epidemiology 1981, 113: 615-622. PMID: 7234849, DOI: 10.1093/oxfordjournals.aje.a113140.Peer-Reviewed Original Research
1980
An evaluation of the usefulness of x-ray pelvimetry: Comparison of the Thoms and modified Ball methods with manual pelvimetry
Fine E, Bracken M, Berkowitz R. An evaluation of the usefulness of x-ray pelvimetry: Comparison of the Thoms and modified Ball methods with manual pelvimetry. American Journal Of Obstetrics And Gynecology 1980, 137: 15-20. PMID: 7369283, DOI: 10.1016/0002-9378(80)90378-6.Peer-Reviewed Original ResearchConceptsX-ray pelvimetryCephalopelvic disproportionCephalic presentationVaginal deliveryPotential oncogenic riskSafe vaginal deliveryObstetric outcomesVertex presentationPrognostic indicatorFetal irradiationOncogenic riskFull trialPelvimetryManual assessmentHigh ratePelvisPresentationDisproportionDeliveryPatientsBall techniqueDiagnosisTrialsAdaptation to and coping with disability one year after spinal cord injury: An epidemiological study
Bracken M, Bernstein M. Adaptation to and coping with disability one year after spinal cord injury: An epidemiological study. Social Psychiatry And Psychiatric Epidemiology 1980, 15: 33-41. DOI: 10.1007/bf00577959.Peer-Reviewed Original ResearchSpinal cord injuryCord injuryAcute spinal cord injuryDisability one yearAcute care hospitalsDisability 1 yearConnecticut patientsCare hospitalFunctional statusSocio-demographic characteristicsComplete resolutionEpidemiological studiesPsychological statusInjuryType of disabilityOne-yearPatientsDisabilityPsychological reactionsYearsStatusHospitalDischargeThe amylase/creatinine clearance ratio in normal pregnancy and pregnancies complicated by pancreatitis, hyperemesis gravidarum, and toxemia
DeVore G, Bracken M, Berkowitz R. The amylase/creatinine clearance ratio in normal pregnancy and pregnancies complicated by pancreatitis, hyperemesis gravidarum, and toxemia. American Journal Of Obstetrics And Gynecology 1980, 136: 747-754. PMID: 6153508, DOI: 10.1016/0002-9378(80)90451-2.Peer-Reviewed Original ResearchConceptsHyperemesis gravidarumEpigastric painClinical diagnosisAmylase/creatinine clearance ratioCreatinine clearance ratioDiagnosis of pancreatitisCaM/Pregnant patientsCreatinine clearanceNonpregnant patientsNonpregnant valuesNormal pregnancyPancreatitisPatientsPregnancyToxemiaGravidarumElevated ratioDiagnosisClearance ratioPainGestationClearanceRelationship between neurological and functional status after acute spinal cord injury: An epidemiological study
Bracken M, Hildreth N, Freeman D, Webb S. Relationship between neurological and functional status after acute spinal cord injury: An epidemiological study. Journal Of Clinical Epidemiology 1980, 33: 115-125. PMID: 7354100, DOI: 10.1016/0021-9681(80)90035-1.Peer-Reviewed Original ResearchConceptsSensory functionMotor functionFunctional statusFirst post-injury yearAcute spinal cord injurySpinal cord injurySelfcare activitiesFour-point scaleADL scoresHospital dischargeHospital admissionSensory lossNeurological functionProspective studyCord injuryDaily livingEpidemiological studiesMovement of limbsHospitalizationPatientsInjuryGreater improvementAdditive effectSignificant improvementStatusAssessment of fetal kidney size in normal gestation by comparison of ratio of kidney circumference to abdominal circumference
Grannum P, Bracken M, Silverman R, Hobbins J. Assessment of fetal kidney size in normal gestation by comparison of ratio of kidney circumference to abdominal circumference. American Journal Of Obstetrics And Gynecology 1980, 136: 249-254. PMID: 7352508, DOI: 10.1016/0002-9378(80)90606-7.Peer-Reviewed Original ResearchConceptsFetal kidney sizeKidney diseaseKidney sizeCircumference measurementsFetal kidneyAbdominal circumference measurementsCongenital kidney diseaseGestational ageThird trimesterNormal gestationAbdominal circumferenceUmbilical veinNormal outcomeAC ratioKidney abnormalitiesIntrarenal anatomyPatientsPregnancyKidneyDiseaseRiskCircumferenceNormal meanDiameter measurementsTrimester
1979
Contraceptive practice and repeat induced abortion: an epidemiological investigation
shepard M, Bracken M. Contraceptive practice and repeat induced abortion: an epidemiological investigation. Journal Of Biosocial Science 1979, 11: 289-302. PMID: 528558, DOI: 10.1017/s0021932000012360.Peer-Reviewed Original ResearchConceptsPrevious abortionContraceptive practicesRepeat abortionProportion of patientsMethod of contraceptionTime of conceptionUnprotected coitusInduced abortionEpidemiological investigationsContraceptionWomenAbortionAbortion experienceImportant predictorExperience of abortionPatientsPregnancyCoitusGreater use
1978
Classification of the severity of acute spinal cord injury: implications for management
Bracken M, Webb S, Wagner F. Classification of the severity of acute spinal cord injury: implications for management. Spinal Cord 1978, 15: 319-326. PMID: 625431, DOI: 10.1038/sc.1977.48.Peer-Reviewed Original ResearchConceptsSpinal cord injuryAcute spinal cord injuryCord injuryMotor functionBrown-Sequard syndromeMotor function scalesPoor motor functionComprehensive neurological examinationDifferent therapeutic modalitiesSevere motor impairmentAcute hospitalisationCord lesionsNeurological examinationFracture dislocationSensory lossProspective studyEmergency departmentHigh prevalenceTherapeutic modalitiesMotor impairmentSensory functionPatientsFunction scaleOlder ageInjury
1973
Abortion counseling: An experimental study of three techniques
Bracken M, Grossman G, Hachamovitch M, Sussman D, Schrieir D. Abortion counseling: An experimental study of three techniques. American Journal Of Obstetrics And Gynecology 1973, 117: 10-20. PMID: 4722367, DOI: 10.1016/0002-9378(73)90721-7.Peer-Reviewed Original Research