2012
Virulence of Streptococcus pneumoniae serotype 6C in experimental otitis media
Sabharwal V, Figueira M, Pelton SI, Pettigrew MM. Virulence of Streptococcus pneumoniae serotype 6C in experimental otitis media. Microbes And Infection 2012, 14: 712-718. PMID: 22414497, PMCID: PMC3382049, DOI: 10.1016/j.micinf.2012.02.008.Peer-Reviewed Original ResearchConceptsAcute otitis mediaExperimental otitis mediaPneumococcal conjugate vaccineOtitis mediaSerotype 6CInvasive pneumococcal diseaseOverall carriage rateLow-density infectionsMiddle ear infectionStreptococcus pneumoniae serotype 6CReplacement serotypesPneumococcal diseaseVaccine serotypesConjugate vaccineNonvaccine serotypesCarriage rateEar infectionsNasopharyngeal colonizationChinchilla modelStreptococcus pneumoniaeHost defenseSerotypesDisease potentialInfectionDisease
2004
Prevalence of the hifBC, hmw1A, hmw2A, hmwC, and hia Genes in Haemophilus influenzae Isolates
Ecevit IZ, McCrea KW, Pettigrew MM, Sen A, Marrs CF, Gilsdorf JR. Prevalence of the hifBC, hmw1A, hmw2A, hmwC, and hia Genes in Haemophilus influenzae Isolates. Journal Of Clinical Microbiology 2004, 42: 3065-3072. PMID: 15243061, PMCID: PMC446296, DOI: 10.1128/jcm.42.7.3065-3072.2004.Peer-Reviewed Original ResearchConceptsAcute otitis mediaOtitis mediaH. influenzaeHia geneHaemophilus influenzaeMiddle earRespiratory tract sitesH. influenzae infectionsAdhesin genesClinical H. influenzaeThroat isolatesInfluenzae infectionNTHi isolatesNasopharyngeal colonizationNTHi strainsType b strainsClinical isolatesPrevalenceInfluenzaeB strainsEpithelial cellsHMW adhesinsType BVirulence factorsHibDiversity and sharing of Haemophilus influenzae strains colonizing healthy children attending day-care centers
FARJO RS, FOXMAN B, PATEL MJ, ZHANG L, PETTIGREW MM, MCCOY SI, MARRS CF, GILSDORF JR. Diversity and sharing of Haemophilus influenzae strains colonizing healthy children attending day-care centers. The Pediatric Infectious Disease Journal 2004, 23: 41-46. PMID: 14743045, DOI: 10.1097/01.inf.0000106981.89572.d1.Peer-Reviewed Original ResearchMeSH KeywordsCarrier StateChild Day Care CentersChild, PreschoolCohort StudiesColony Count, MicrobialDNA, BacterialElectrophoresis, Gel, Pulsed-FieldFemaleGenotypeHaemophilus InfectionsHaemophilus influenzaeHumansIncidenceMaleMass ScreeningMichiganOtitis MediaPolymerase Chain ReactionReference ValuesRisk AssessmentSerotypingConceptsDay care centersH. influenzaeHealthy childrenH. influenzae organismsAcute otitis mediaH. influenzae colonizationH. influenzae strainsUnique strainsEnterobacterial repetitive intergenic consensus PCRThroat culturesOtitis mediaInitial screening techniqueNasopharyngeal colonizationPrevalence ratesColonizing strainsHaemophilus influenzaeHeterogeneity of strainInfluenzaeConsensus PCRRate of colonizationChildrenField gel electrophoresisSame strainPathogenic microorganismsEvidence of sharing